Background: Fatty liver disease is also known as fatty liver syndrome and is also called hepatic steatosis the aim of this study was to evaluate the effect of eight weeks of aerobic exercise and probiotic intake on FOXA1 gene expression in rats with fatty liver. Methods: This study is an experimental laboratory study. Thirty-two male wistar rats were divided into 4 groups of 8 in the healthy, steatosis, steatosis + probiotic, steatosis + probiotic +aerobic exercise groups and tested for 8 weeks. The exercise protocol was as follows: in the first week from 10 minutes of running at a speed of 18 meters per minute to the eighth week with 60 minutes of running at a speed of 28 meters per minute. Consumption of probiotics; Relevant groups received 109 CFU / ml of Lactobacillus rhamnosus GG by gavage daily for 5 weeks and 5 days a week. RT-pcr method was used to evaluate the expression of FOXA1gene. ANOVA were used for data analysis using SPSS 23 software at a significant level (p <0.05). Results: The results showed that eight weeks of aerobic exercise with probiotic intake had a significant decrease on the expression of FOXA1 gene and LDL in rats with fatty liver (P <0.05). Conclusion: According to the results of the study, It seems that aerobic exercise with probiotics intake can improve the liver function of non-alcoholic fatty liver patients. Manuscript profile

Background: The Aim of The Study Was to Investigate the Effect of Selected Taekwondo Exercises and Ginseng Supplement Consumption on Body Composition and Some Selected Factors of Physical and Movement Fitness of Overweight Girls. Materials and Methods: The Research Is a Semi-Experimental Research That Was Conducted in The Field Method, For This Purpose, 28 Overweight Girls Interested in Taekwondo in Tehran, Who Had At Least Three Years of Taekwondo Experience. By Cluster Sampling Method and Using G-POWER Software, They Were Selected Purposefully and Randomly Divided Equally in to Four Experimental and Control Groups of Seven People. Taekwondo Training Program as Well as HIIT Training Program Including 8 Weeks of Training Were Implemented. HIIT Training Includes a rest Test, Meaning 6 Intervals Of 35 Meters, With A 10-Second Rest At The End Of Each Interval. After Eight Weeks of Training, All Dependent Variables of The Research Were Measured Using Standard Tests in The Statistics Section, T Test, Variance Analysis and LSD Post Hoc Test Were Used. Results: The Results of One-Way Analysis of Variance (ANOVA) Showed that the Percentage of Body Fat in The Experimental Groups Decreased Compared to The Control Group and Showed a Significant Difference (P≤0.05). Also, In the Supplement Group, Due to The Consumption of Ginseng Supplement and Its Relationship with The Increase in Muscle Volume and Strength, An Increase in Sargent's Jump Was Reported (P≤0.05). Conclusion: It Was Found that the Reason Can Be Considered the Nature of The HIIT Exercise That Has Been Performed Under High Pressure. Manuscript profile