Subject Areas : Sport Physiology
Faezeh Saebi
1
,
Shahram Gholamrezaei Darsara
2
,
Mohammad Ali Azarbayjani
3
,
Mohammad Reza Fadaei Chafi
4
1 - Department of Physical Education and Sports Sciences, Ra.C., Islamic Azad University, Rasht, Iran.
2 - Department of Physical Education and Sports Sciences, Ra.C., Islamic Azad University, Rasht, Iran.
3 - Department of Physical Education and Sport Sciences, CT.C., Islamic Azad University, Tehran, Iran.
4 - Department of Physical Education and Sports Sciences, Ra.C., Islamic Azad University, Rasht, Iran.
Keywords:
Abstract :
1-Zhang X, Liu J, Ni Y, Yi C, Fang Y, Ning Q, Shen B, Zhang K, Liu Y, Yang L, Li K, Liu Y, Huang R, Li Z. Global Prevalence of Overweight and Obesity in Children and Adolescents: A Systematic Review and Meta-Analysis. JAMA Pediatr. 2024 Aug 1;178(8):800-813.
2-GBD 2021 Adult BMI Collaborators. Global, regional, and national prevalence of adult overweight and obesity, 1990-2021, with forecasts to 2050: a forecasting study for the Global Burden of Disease Study 2021. Lancet. 2025 Mar 8;405(10481):813-838.
3- Xu R, Wang X-j, Lin Q-c, Zhuang Y-t, Zhou Q-y, Xu N-f and Zheng D-q (2024) Trends and projections of the burden of disease for male infertility in China from 1990 to 2021: an analysis from the Global Burden of Disease 2021 study. Front. Reprod. Health 6:1501675.
4- Sengupta P, Borges E Jr, Dutta S, Krajewska-Kulak E. Decline in sperm count in European men during the past 50 years. Hum Exp Toxicol. 2018 Mar;37(3):247-255.
5- Katib A. Mechanisms linking obesity to male infertility. Cent European J Urol. 2015;68(1):79-85.
6- Teerds KJ. Functional relationship between obesity and male reproduction: from humans to animal models. Hum Reprod Update. 2011;17:667–683.
7- Michalakis K, Mintziori G. The complex interaction between obesity, metabolic syndrome and reproductive axis: a narrative review. Metabolism. 2013;62:457–478.
8- Mihalca R, Fica S. The impact of obesity on the male reproductive axis. J Med Life. 2014 Jun 15;7(2):296-300.
9- Mushannen T, Cortez P, Stanford FC, Singhal V. Obesity and Hypogonadism-A Narrative Review Highlighting the Need for High-Quality Data in Adolescents. Children (Basel). 2019 May 1;6(5):63.
10-Cooper LA, Page ST, Amory JK, Anawalt BD, Matsumoto AM. The association of obesity with sex hormone-binding globulin is stronger than the association with ageing--implications for the interpretation of total testosterone measurements. Clin Endocrinol (Oxf). 2015 Dec;83(6):828-33.
11-Zhao JL, Zhao YY, Zhu WJ. A high-fat, high-protein diet attenuates the negative impact of casein-induced chronic inflammation on testicular steroidogenesis and sperm parameters in adult mice. Gen Comp Endocrinol. 2017 Oct 1;252:48-59.
12- Wang J, Zhang S, Hu L, Wang Y, Liu K, Le J, Tan Y, Li T, Xue H, Wei Y, Zhong O, He J, Zi D, Lei X, Deng R, Luo Y, Tang M, Su M, Cao Y, Liu Q, Tang Z, Lei X. Pyrroloquinoline quinone inhibits PCSK9-NLRP3 mediated pyroptosis of Leydig cells in obese mice. Cell Death Dis. 2023 Nov 7;14(11):723.
13- Miller WL, Auchus RJ. The molecular biology, biochemistry, and physiology of human steroidogenesis and its disorders[J]. Endocr Rev. 2011;32(1):81‐151.
14- Su X, Lin D, Luo D, Sun M, Wang X, Ye J, Zhang M, Zhang Y, Xu X, Yu C, Guan Q. Cyclophilin D participates in the inhibitory effect of high-fat diet on the expression of steroidogenic acute regulatory protein. J Cell Mol Med. 2019 Oct;23(10):6859-6871.
15- Qi X, Zhang M, Sun M, Luo D, Guan Q, Yu C. Restoring Impaired Fertility Through Diet: Observations of Switching From High-Fat Diet During Puberty to Normal Diet in Adulthood Among Obese Male Mice. Front Endocrinol (Lausanne). 2022 Apr 19;13:839034.
16- Campos-Silva P, Costa WS, Sampaio FJB, Gregorio BM. Prenatal and/or postnatal high-fat diet alters testicular parameters in adult Wistar Albino rats. Histol Histopathol. 2018 Apr;33(4):407-416
17- Lalrinzuali S, Khushboo M, Dinata R, Bhanushree B, Nisa N, Bidanchi RM, Laskar SA, Manikandan B, Abinash G, Pori B, Roy VK, Gurusubramanian G. Long-term consumption of fermented pork fat-based diets differing in calorie, fat content, and fatty acid levels mediates oxidative stress, inflammation, redox imbalance, germ cell apoptosis, disruption of steroidogenesis, and testicular dysfunction in Wistar rats. Environ Sci Pollut Res Int. 2023 Apr;30(18):52446-52471.
18- Yi X, Gao H, Chen D, Tang D, Huang W, Li T, Ma T, Chang B. Effects of obesity and exercise on testicular leptin signal transduction and testosterone biosynthesis in male mice. Am J Physiol Regul Integr Comp Physiol. 2017 Apr 1;312(4):R501-R510.
19- Xu Z, Qin Y, Lv B, Tian Z, Zhang B. Effects of Moderate-Intensity Continuous Training and High-Intensity Interval Training on Testicular Oxidative Stress, Apoptosis and m6A Methylation in Obese Male Mice. Antioxidants (Basel). 2022 Sep 21;11(10):1874.
20- Od-Ek P, Deenin W, Malakul W, Phoungpetchara I, Tunsophon S. Anti-obesity effect of Carica papaya in high-fat diet fed rats. Biomed Rep. 2020 Oct;13(4):30.
21- Hornberger, T. A., Jr., & Farrar, R. P. (2004). Physiological hypertrophy of the FHL muscle following eight weeks of progressive resistance exercise in the rat. Can J Appl Physiol, 29(1), 16-31.
22- Ferlin A, Selice R, Carraro U, Foresta C. Testicular function and bone metabolism–beyond testosterone[J]. Nat Rev Endocrinol. 2013;9(9):548‐554.
23- Beattie MC, Adekola L, Papadopoulos V, Chen H, Zirkin BR. Leydig cell aging and hypogonadism[J]. Exp Gerontol. 2015;68:87‐91.
24- Miller WL, Auchus RJ. The molecular biology, biochemistry, and physiology of human steroidogenesis and its disorders[J]. Endocr Rev. 2011;32(1):81‐151.
25- Stocco DM. Clinical disorders associated with abnormal cholesterol transport: mutations in the steroidogenic acute regulatory protein[J]. Mol Cell Endocrinol. 2002;191(1):19‐25.
26- Hales DB, Allen JA, Shankara T, et al. Mitochondrial function in Leydig cell steroidogenesis. Ann N Y Acad Sci. 2005;1061:120‐134.
27- Han J, Zhao C, Guo H, Liu T, Li Y, Qi Y, Deussing JM, Zhang Y, Tan J, Han H, Ma X. Obesity induces male mice infertility via oxidative stress, apoptosis, and glycolysis. Reproduction. 2023 May 26;166(1):27-36.
28- Fayaz SM, Raj YV, Krishnamurthy RG. CypD: the key to the death door[J]. CNS Neurol Disord Drug Targets. 2015;14(5):654‐663.
29- Basso E, Fante L, Fowlkes J, Petronilli V, Forte MA, Bernardi P. Properties of the permeability transition pore in mitochondria devoid of Cyclophilin D[J]. J Biol Chem. 2005;280(19):18558‐18561.
30- Antoniel M, Giorgio V, Fogolari F, Glick G, Bernardi P, Lippe G. The oligomycin‐sensitivity conferring protein of mitochondrial ATP synthase: emerging new roles in mitochondrial pathophysiology[J]. Int J Mol Sci. 2014;15(5):7513‐7536.
31- Yi X, Tang D, Cao S, Li T, Gao H, Ma T, Yao T, Li J, Chang B. Effect of Different Exercise Loads on Testicular Oxidative Stress and Reproductive Function in Obese Male Mice. Oxid Med Cell Longev. 2020 Jan 27;2020:3071658.
