Application of Aerogels in Wound Dressings
Subject Areas :
Mohammad Hossein Karami
1
(Department of Nanotechnology and Advanced Materials, Materials and Energy Research Center, Karaj, Iran)
Ali Zamanian
2
(Department of Nanotechnology and Advanced Materials, Materials and Energy Research Center, Karaj, Iran)
Keywords: Aerogel, Wound Dressing, Antibacterial, Chitosan, Composite,
Abstract :
Aerogels are lightweight solid materials that are made from organic or inorganic materials, or as composites, and are being studied as advanced materials for various applications. The use of aerogels in everyday applications is limited due to their high cost and complex preparation process. Drying aerogels can be laborious, requiring significant energy and resources. When prepared as composites, aerogels can enhance mechanical properties. They can also be tailored to release bioactive molecules, such as growth factors or antibiotics, to speed up the healing process. However, there are challenges in using aerogels for wound healing. Large-scale production may be costly, limiting their use in clinical settings. Additionally, the mechanical properties of aerogels may not be suitable for all wound types. Further research is needed to overcome these challenges and optimize the use of aerogels in clinical settings. This research investigates different types of wound dressings, commercial wound dressings, chitosan-based aerogels, and the properties and applications of aerogels in wound dressings. The unique properties of aerogels, such as their high porosity, large surface area, and biocompatibility, make them ideal candidates for enhancing the wound healing process. Studies have shown that aerogels made from chitosan can improve cell adhesion, proliferation, and migration, resulting in quicker and more efficient wound closure. Furthermore, the controlled release of bioactive molecules from aerogels can further improve the healing process by reducing inflammation and promoting tissue regeneration.
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