List of Articles Aerobic exercise

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  1 - Moderate aerobic exercise and probiotic intake on FOXA1 gene expression in non-alcoholic fatty liver animal model: An Experimental Study
  Shahin Riyahi Malayeri Hamzeh  MohamMadi Firooz Abad Omid   Soleimani Ghaleh Soheila   Azarkhosh
  10.61186/jspac.36413.2.4.14
  Background: Fatty liver disease is also known as fatty liver syndrome and is also called hepatic steatosis the aim of this study was to evaluate the effect of eight weeks of aerobic exercise and probiotic intake on FOXA1 gene expression in rats with fatty liver. Metho More

  Background: Fatty liver disease is also known as fatty liver syndrome and is also called hepatic steatosis the aim of this study was to evaluate the effect of eight weeks of aerobic exercise and probiotic intake on FOXA1 gene expression in rats with fatty liver. Methods: This study is an experimental laboratory study. Thirty-two male wistar rats were divided into 4 groups of 8 in the healthy, steatosis, steatosis + probiotic, steatosis + probiotic +aerobic exercise groups and tested for 8 weeks. The exercise protocol was as follows: in the first week from 10 minutes of running at a speed of 18 meters per minute to the eighth week with 60 minutes of running at a speed of 28 meters per minute. Consumption of probiotics; Relevant groups received 109 CFU / ml of Lactobacillus rhamnosus GG by gavage daily for 5 weeks and 5 days a week. RT-pcr method was used to evaluate the expression of FOXA1gene. ANOVA were used for data analysis using SPSS 23 software at a significant level (p <0.05). Results: The results showed that eight weeks of aerobic exercise with probiotic intake had a significant decrease on the expression of FOXA1 gene and LDL in rats with fatty liver (P <0.05). Conclusion: According to the results of the study, It seems that aerobic exercise with probiotics intake can improve the liver function of non-alcoholic fatty liver patients. Manuscript profile
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  2 - Effect of Aerobic Training along with Garlic on Oxidative Stress Index in Obese Women with High Blood Pressure
  Ghasem  Torabi Palat Kaleh Mostafa  Kazemi Ahmad Abdi Asieh   Abbassi Daloii Masoomeh Alsadat Mirshafaei
  10.61186/jspac.38796.2.5.1
  Background: A large amount of evidence shows that oxidative stress plays a central role in hypertension pathophysiology. The aim of this study was to examine effect of aerobic training along with Garlic on oxidative stress index in obese women with high blood pressure. More

  Background: A large amount of evidence shows that oxidative stress plays a central role in hypertension pathophysiology. The aim of this study was to examine effect of aerobic training along with Garlic on oxidative stress index in obese women with high blood pressure. Materials and Methods: In this clinical trial study, 36 postmenopausal obese women with hypertension were purposefully and accessibly selected from Sari and were simple randomly divided into four groups Control (C), Aerobic Training (AT), Garlic (G) and Aerobic Training +Garlic (ATG). The training groups participated in a progressive aerobic training for eight weeks, three sessions a week (55% to 65% of the reserved heart rate and for 30 to 55 min). The groups of G and ATG were provided 1000 mg of garlic supplement for eight weeks (After breakfast and dinner). Two days before and after the protocol, blood samples were taken in fasting state. SPSS 16.0 software was used for statistical analysis. Data were analyzed using ANCOVA at p<0.05. Results: The results showed that the levels of malondialdehyde (MDA) (P=0.0001) decrease significantly in the experimental groups. Also, superoxide dismutase (SOD) (P=0.001), glutathione peroxidase (GPX) (P=0.000) and catalase (CAT) (P=0.001) in the experimental groups increased significantly compared to the C group. The amount of SOD, GPx and CAT in the ATG group was significantly higher than the AT and G group (p≤0/05). Conclusion: It seems that AT and G has interactive effects on reducing Oxidative Stress in obese women with high blood pressure. Manuscript profile
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  3 - The effect of exercise and vitamin B6 on the expression of COX2 and IL-1B genes in endometrial tissue of endometriosis rats
  Fatemeh Rashidpour Parvin  Farzanegi Hajar   Abbaszadeh
  10.61186/jspac.39258.2.6.31
  Background: Endometriosis is a chronic disease, afflicting about 5-10% of women. Many possible environmental and molecular factors have been proposed for the pathogenesis of endometriosis; nevertheless, its real mechanism is still under investigation. This research aime More

  Background: Endometriosis is a chronic disease, afflicting about 5-10% of women. Many possible environmental and molecular factors have been proposed for the pathogenesis of endometriosis; nevertheless, its real mechanism is still under investigation. This research aimed to examine the effect of physical exercise and B6 vitamin on the expression of COX2 and IL-1B genes on endometriotic tissue in endometriosis model rats. Materials and Methods: In this experimental research, 25 Wistar rats were randomly assigned into five groups: control-healthy, endometriosis, endometriosis + exercise, endometriosis + B6, endometriosis + exercise + B6. Vitamin B6 were administered as 60 mg/kg per body weight of each rat. The swimming exercise program involved 8 weeks of exercise, each week 5 days, and each day for 30 min. For data analysis, one-way analysis of variance (ANOVA) and post hoc Tukey test were used. Results: The extent of expression of COX and IL-1β genes increased significantly in the endometriosis group compared to the control-healthy group. All three groups of endometriosis + exercise, endometriosis + B6, and endometriosis + exercise + B6 showed a significant reduction of COX2 expression compared to the endometriosis group. Two groups of endometriosis + exercise and endometriosis + exercise + B6 indicated a significant decline in the extent of expression of 1L-1β gene, as compared to the endometriosis group. The endometriosis + exercise + B6 group revealed a significant reduction in the extent of expression of COX2 and IL-1β genes compared to endometriosis + B6. Finally, the endometriosis + exercise group revealed a significant decrease in the extent of expression of IL-1β gene, when compared with the endometriosis + B6. Conclusion: Overall, the results suggest that changes in the key molecules or signaling pathways as well as gene expression in the endometriosis process can contribute to improving this condition. Doing physical activity and concurrent consumption of B6 vitamin will be helpful in curbing this disease and improving the level of this condition. Manuscript profile
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  4 - The effect of eight weeks of aerobic training on some apoptotic factors of elderly men
  Seyed Hossein  Mousavi Bahram  Abedi Mojtaba Khansooz
  Background: Considering the significant increase in apoptosis in the elderly, which is related to cardiovascular diseases, cancer, etc. The purpose of this research was to investigate the effect of eight weeks of aerobic exercise on some factors of apoptosis in elderly More

  Background: Considering the significant increase in apoptosis in the elderly, which is related to cardiovascular diseases, cancer, etc. The purpose of this research was to investigate the effect of eight weeks of aerobic exercise on some factors of apoptosis in elderly men was investigated. Materials and Methods: This research was conducted using a semi-experimental method with 30 healthy elderly men aged 60 to 75 years. who voluntarily participated in this research project and were randomly divided into two experimental (15 people) and control (15 people) groups. The experimental group participated in aerobic exercises for 8 weeks (three sessions of 1 hour per week) based on the special recommendations of the American College of Sports Medicine (ACSM) for the elderly. The control group did not have any physical activity during this period. Serum caspase-8, P53 and IGF-1 were measured by ELISA method. Dependent t-test and independent t-test were used to check the intra-group and inter-group differences of variables. Data analysis was done using SPSS version 20 software and the significance level was considered p≤0.05 in all steps. Results: The results showed that eight weeks of aerobic exercise increased the serum levels of caspase 8(P=0.0001) and decreased the serum levels of P53(P=0.0001) and IGF-1(insulin-like growth factor) (P=0.0001). Conclusion: According to the findings of the present research, it seems that eight weeks of aerobic exercise significantly increases the serum levels of caspase 8 and decreases the serum levels of P53 and IGF-1 in elderly men. According to these results, more research is needed in this field. Manuscript profile
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  5 - Investigating the effect of aerobic exercise and octopamine on HIF-1 gene and protein expression and the permeability of white cells into visceral adipose tissue in rats fed with heated oil
  Fateme  Shokri Mohammad Ali  Azarbayjani Maghsoud Peeri Farshad Ghazalian
  Background and purpose: the use of heated oils has become an integral part of today's nutrition. Studies show that with the development of obesity, capillarization in adipose tissue does not occur in line with changes in cell size. Therefore, adipose tissue in obese peo More

  Background and purpose: the use of heated oils has become an integral part of today's nutrition. Studies show that with the development of obesity, capillarization in adipose tissue does not occur in line with changes in cell size. Therefore, adipose tissue in obese people is always associated with lack of oxygen and it causes systemic inflammation by releasing inflammatory mediators. The purpose of this study is to investigate the effect of aerobic exercise and octopamine on HIF-1 protein concentration in visceral fat and white cells in rats fed with deeply-heated oil. Methodology: In an experimental trial, 30 male Wistar rats were divided into five groups: healthy control, control-heated oil, aerobic exercise-heated oil, octopamine-heated oil and exercise, and octopamine-heated oil. Octopamine was given to rats by IP intraperitoneal injection daily for four weeks and five days a week. Aerobic exercise was also performed for four weeks and five days a week with moderate intensity on the treadmill. Forty-eight hours after the last intervention, the rats were anesthetized and visceral adipose tissue was removed from the body to measure HIF-1a gene expression. As a result of receiving deeply-heated oil, the expression of HIF-1 gene and protein in visceral fat increased significantly (P=0.001), but the number of white cells in visceral adipose tissue increased significantly (P=0.001). Aerobic exercise significantly decreased HIF-1 gene and protein expression (P=0.01). In addition, octopamine supplementation had no significant effect on HIF-1 gene expression of visceral fat of white cells in rats poisoned with deeply-heated oil. Receiving octopamine also decreased HIF-1 gene and protein expression (P=0.002). In addition, exercise significantly reduced the number of white cells (P=0.001). Octopamine could significantly reduce the expression of HIF-1 protein and the number of white cells. The interaction of exercise and octopamine was significant for the expression of HIF-1 protein and the number of white cells. Findings: The results of this study showed that aerobic exercise and octopamine improve the angiogenesis process of the visceral adipose tissue that had been disrupted by heated oils, and reduce the damage caused by feeding with deeply-heated oils. Manuscript profile
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  6 - The effect of 8 weeks of aerobic exercise and papaya supplementation on lipid profile of men with fatty liver in Yazd city
  leila   Rahimi Abbas   Fattahi Bafghi Seyed Abbas  Hoseini Motlagh
  Background: Today, researches have shown that the combination of some herbal supplements and doing sports exercises can have more effects on the recovery of some diseases. Therefore, the purpose of this research is to investigate the effect of eight weeks of aerobic tra More

  Background: Today, researches have shown that the combination of some herbal supplements and doing sports exercises can have more effects on the recovery of some diseases. Therefore, the purpose of this research is to investigate the effect of eight weeks of aerobic training and papaya supplement consumption on the lipid profile of men with fatty liver. Materials and Methods: The statistical population of the present study included all men with fatty liver in Yazd city, among whom there were 60 men with an average age of 25 to 35 years and a body mass index between 25 and 35 kg/m2, were randomly divided into four groups of 15 including aerobic exercise group, aerobic exercise group-papaya supplement, papaya supplement group and control group. The subjects of the training and training-supplementary group performed aerobic exercise according to the given program for eight weeks, three sessions per week and each session lasted for 70 minutes. In the same period, the supplement and training groups also received a papaya supplement in the form of capsules at a dose of 30 mg per kilogram of body weight every day after dinner. Karika Papaya Slim capsules produced in the Philippines in 2021 were prepared. Blood samples were taken from the subjects in the fasting state and at night, 72 hours before and after 8 weeks of training. Data analysis at the level of descriptive statistics using mean and standard deviation tests and at the level of inferential statistics after checking the normality of the data by the Shapiro-Wilk test. Two-way analysis of variance and Tukey's post hoc test were used. A significant level was considered in the current research (P<0.05) and all statistical steps were performed using spss25. Results: he present study showed that eight weeks of aerobic training with papaya supplementation had a significant effect on serum levels of low-density lipoprotein (LDL), high-density lipoprotein (HDL), and triglycerides (TG) However, there was no significant change in the level of cholesterol (TC) (P>0.05). Conclusion: Based on the results obtained from the present research, it is possible to use aerobic exercise and papaya supplement separately and especially simultaneously to improve the lipid profile of patients with fatty liver. Manuscript profile
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  7 - The effect of eight weeks of crocetin consumption and aerobic exercise on the expression of Myod in the heart tissue of elderly prediabetic rats
  Abolhasan  Sharifi Rigi Khosro   Jalali Dehkordi Mohsen   Akbarpour Beni Farzaneh   Taghian
  Background: Diabetic cardiomyopathy refers to changes in the heart as a result of impaired glucose homeostasis, leading to ventricular dysfunction and associated with mitochondrial dysfunction. Since sports activity is known to protect the heart, the aim of the present More

  Background: Diabetic cardiomyopathy refers to changes in the heart as a result of impaired glucose homeostasis, leading to ventricular dysfunction and associated with mitochondrial dysfunction. Since sports activity is known to protect the heart, the aim of the present study was to investigate aerobic exercise and the effective substance crocetin on the expression of Myod gene in the heart tissue of an experimental model of elderly prediabetic rats. Materials and Methods: In this experimental trial, 25 elderly female c57bl6 male mice with prediabetes (20 mg/kg peritoneal injection) aged 14-16 weeks and weighing 30-35 grams were divided into 5 healthy control groups, prediabetic, prediabetic + aerobic exercise, pre-diabetic + crocetin, pre-diabetic + aerobic exercise + crocetin were divided. aerobic training was performed for eight weeks, five sessions per week. Mice received crocetin 30 mg/kg/day by intraperitoneal injection. Myod expression was measured by Real Time PCR method. To analyze the data, one-way analysis of variance and Tukey's post hoc test were used (P≥0.05). Results: Myod gene expression was significantly decreased in the prediabetic group compared to the healthy group (P=0.01). Myod gene expression was significantly higher in the pre-diabetes group + aerobic exercise + crocetin supplement and diabetes group + aerobic exercise + crocetin supplement than other groups (P=0.01). Conclusion: It seems that intermittent aerobic exercise and crocetin both alone and simultaneously are effective in improving Myod gene expression in prediabetic heart tissue. Therefore, the use of periodic aerobics and crocetin n is recommended in pre-diabetes conditions of old age Manuscript profile