List of Articles diabetes

• Open Access Article
  • Abstract Page
  • Full-Text
  
  1 - The effect of eight weeks of High Intensity Interval Training (HIIT) on the expression of lipasin in diabetic rats
  Sepideh Salehi Nikoo   khosravi
  10.61186/jspac.38685.2.5.73
  Background: Diabetes is a metabolic disorder recognized as one of the most common diseases in the world. The disease has also increased dramatically in Iran.Today, there are many ways to treat diabetes, one of which is the increase in the level of pancreatic beta cells. More

  Background: Diabetes is a metabolic disorder recognized as one of the most common diseases in the world. The disease has also increased dramatically in Iran.Today, there are many ways to treat diabetes, one of which is the increase in the level of pancreatic beta cells. The increase in these cells is done in several ways Several studies have demonstrated that the lipasin or betatrophin gene, a liver-expressed peptide hormone, increases the proliferation of beta cells, and that overexpression of this gene can increase the number of beta cells. Materials and Methods: The study was conducted on 16 Wistar rats with a mean weight of 160 ± 10. They were induced by diabetes (seven months of diabetes mellitus was caused in rats). They then were divided into two groups of 6: Control (C) and High-Intensity Interval Training (HIIT). Eight weeks of exercise training was conducted on rats.The qRT-PCR technique was used to investigate changes in lipasin expression. An Independent t-test was used for data analysis, and Pearson correlation was used to determine the correlation between lipasin expression and insulin resistance index (P <0.05). Results: The results showed that expression of lipasin gene in the liver of rats in the training group was significantly higher than the control group rats after 8 weeks of training; Insulin resistance index of plasma, plasma insulin and plasma glucose decreased considerably after eight weeks of HIIT. Between lipasin expression and insulin resistance index in rats with type 2 diabetes in the training group, a consider correlation has been observed. Conclusion: This study showed that an 8-week HIIT training period, with increased lipasin expression, could increase beta cells and also recover type 2 diabetes, which had been destroyed by these cells, and as a result of this increase in Insulin secretion and there is a way to prevent the disease. Manuscript profile
• Open Access Article
  • Abstract Page
  • Full-Text
  
  2 - A new approach to IoT-based disease diagnosis using genetic algorithms and various classifiers
  seyed ebrahim dashti maryam nikpor mehdi nikpor mahbobe johari
  Medical information technology and health services are related to the national welfare and livelihood of the people. The integration of cloud computing and the Internet of Things will be a major breakthrough in modern medical applications. This study focuses on the chro More

  Medical information technology and health services are related to the national welfare and livelihood of the people. The integration of cloud computing and the Internet of Things will be a major breakthrough in modern medical applications. This study focuses on the chronic disease of diabetes, which is one of the leading causes of death worldwide. This research has applied medical information technology in the field of IoT, especially in the field of medical monitoring and management applications. A model architecture for remote monitoring and management of the health information cloud platform is proposed and analyzed, and then an algorithm based on genetic algorithm and hybrid classification for the diagnosis of diabetes is proposed for medical monitoring. The results show that the proposed method has a higher performance than the basic methods and has reached an accuracy of 94%. Manuscript profile
• Open Access Article
  • Abstract Page
  • Full-Text
  
  3 - The effect of a period of Pilates and the supplementation of Royal Jelly on inflammatory indexes of diabetic obese women
  Neda Romuzi
  10.52547/jspac.39953.3.7.63
  Background: The use of supplements, herbal extracts, and exercise training for the treatment of diseases and metabolic disorders has increased among people. Thus, the aim of this study was the study of The effect of a period of Pilates and the supplementation of Royal More

  Background: The use of supplements, herbal extracts, and exercise training for the treatment of diseases and metabolic disorders has increased among people. Thus, the aim of this study was the study of The effect of a period of Pilates and the supplementation of Royal Jelly on inflammatory indexes of diabetic obese women. Materials and Methods: In this quasi-experimental study 44 volunteer diabetic obese women participated and They were randomly divided into Four groups of 11 controls, Royal Jelly, Pilates, Pilates + Royal Jelly. Pilates exercise training was performed during 8 weeks (3 sessions per week, 60 min per session). The subjects consumed a supplement group of 1000 mg of royal Jelly daily for 8 weeks. covariance analysis test were used to examine the in-group differences and between the research groups. Results: The results showed that eight weeks of Pilates and Royal Jelly Supplements significantly reduced the TNF-α, CRP and IL-6 diabetic women(P=0.001). In addition, serum glucose and serum insulin also decreased significantly in during eight weeks of Pilates and supplementation of the royal Jelly(P=0.001). Vo2max significantly Increase in training, training + supplement groups (P=0.001). Conclusion: According to obtained results, it appears that Pilates training plus Royal Jelly extract consumption have better effect on serum inflammatory factors in obsess women with diabetes type 2 Manuscript profile
• Open Access Article
  • Abstract Page
  • Full-Text
  
  4 - Relationship between erythropoietin and fasting glucose glucose after a resistance training program in male Wistar rats with type 2 diabetes
  Farshad   Sadeghi Yaser Kazemzadeh Abdolali  Banaeifar Sajad Arshadi
  Background: Erythropoietin is known as a strong stimulant in the activation of satellite cells and increasing the regeneration function of muscle tissue. The purpose of this study was to investigate the relationship between erythropoietin concentration and fasting blood More

  Background: Erythropoietin is known as a strong stimulant in the activation of satellite cells and increasing the regeneration function of muscle tissue. The purpose of this study was to investigate the relationship between erythropoietin concentration and fasting blood glucose after a resistance training program in male Wistar rats with type 2 diabetes. Materials and Methods: Twenty-four male rats aged 6 weeks were divided into 3 groups: healthy control (n=8), diabetic control (n=8) and resistance training (n=8). Resistance exercises were performed for 8 weeks, 5 sessions per week, with an intensity of 100-30% of the weight of the rats in the resistance training group. In the last week of the training program, the maximum oxygen consumption of the rats was taken using the executive protocol on the rat treadmill. 48 hours after finishing the training program, blood samples were taken from the right ventricle of heart of the rats and erythropoietin and fasting blood glucose were evaluated. The data was statistically analyzed using Pearson's correlation and one-way analysis of variance at the alpha level of less than 0.05. Results: The results showed that there is no significant relationship between erythropoietin and fasting blood glucose among any of the groups. Also, performing 8 weeks of resistance training in diabetic rats led to an increase in erythropoietin concentration (P≤0.0001) and a decrease in blood glucose (P≤0.0001). Conclusion: It seems that more stimulation of EPO and regeneration of muscle tissue as well as increased energy consumption in muscle tissue is one of the possible mechanisms of blood glucose reduction caused by 8 weeks of resistance training in diabetic rats Manuscript profile