List of Articles Probiotic

• Open Access Article
  • Abstract Page
  • Full-Text
  
  1 - The effect of aerobic training and probiotic intake on gene ICAM–1 expression in rats with nonalcoholic fatty liver
  Samaneh  Hadipour Ahmadi Abdolrasoul  Daneshjoo
  10.61186/jspac.19946.1.1.54
  Background: Cell adhesion molecules mediate leukocyte responses to inflammation. The purpose of study was to the effect of aerobic training and probiotic intake on ICAM–1 in rats with fatty liver. Materials and Methods: In this experimental study, 32 rats (200-250 gr) More

  Background: Cell adhesion molecules mediate leukocyte responses to inflammation. The purpose of study was to the effect of aerobic training and probiotic intake on ICAM–1 in rats with fatty liver. Materials and Methods: In this experimental study, 32 rats (200-250 gr) were randomly divided into four groups (healthy control, steatosis, steatosis + probiotic, steatosis + probiotic + training). To create a fatty liver model, tetracycline at a dose of 100 mg / kg in a volume of 1.5 cc was gavaged daily for two weeks. The training program includes 8 weeks and 5 sessions per week, in the initial week with a speed of 18 meters per minute, time started 10 minutes and every week quickly, 1-2 meters per minute and time was added to 10 minutes. Supplemental groups received 109 CFU / ml of Lactobacillus ramensus by gavage daily for 8 weeks and 5 days per week. Liver tissue samples were taken to examine the expression of ICAM-1 gene. 10 ml of blood was collected from the hearts of rats for ALP testing. The data was analyzed using one-way analysis of variance (ANOVA) p05/0≥. Results: The results showed that the aerobic training along with probiotic consumption significantly reduced the expression gene of ICAM-1 and ALP in rats with non-alcoholic fatty liver. Conclusion: It seems aerobic training combined with probiotic consumption improved the expression gene of ICAM-1 and ALP enzyme in the studied samples which can be effective in treating patients with fatty liver disease Manuscript profile
• Open Access Article
  • Abstract Page
  • Full-Text
  
  2 - Moderate aerobic exercise and probiotic intake on FOXA1 gene expression in non-alcoholic fatty liver animal model: An Experimental Study
  Shahin Riyahi Malayeri Hamzeh  MohamMadi Firooz Abad Omid   Soleimani Ghaleh Soheila   Azarkhosh
  10.61186/jspac.36413.2.4.14
  Background: Fatty liver disease is also known as fatty liver syndrome and is also called hepatic steatosis the aim of this study was to evaluate the effect of eight weeks of aerobic exercise and probiotic intake on FOXA1 gene expression in rats with fatty liver. Metho More

  Background: Fatty liver disease is also known as fatty liver syndrome and is also called hepatic steatosis the aim of this study was to evaluate the effect of eight weeks of aerobic exercise and probiotic intake on FOXA1 gene expression in rats with fatty liver. Methods: This study is an experimental laboratory study. Thirty-two male wistar rats were divided into 4 groups of 8 in the healthy, steatosis, steatosis + probiotic, steatosis + probiotic +aerobic exercise groups and tested for 8 weeks. The exercise protocol was as follows: in the first week from 10 minutes of running at a speed of 18 meters per minute to the eighth week with 60 minutes of running at a speed of 28 meters per minute. Consumption of probiotics; Relevant groups received 109 CFU / ml of Lactobacillus rhamnosus GG by gavage daily for 5 weeks and 5 days a week. RT-pcr method was used to evaluate the expression of FOXA1gene. ANOVA were used for data analysis using SPSS 23 software at a significant level (p <0.05). Results: The results showed that eight weeks of aerobic exercise with probiotic intake had a significant decrease on the expression of FOXA1 gene and LDL in rats with fatty liver (P <0.05). Conclusion: According to the results of the study, It seems that aerobic exercise with probiotics intake can improve the liver function of non-alcoholic fatty liver patients. Manuscript profile
• Open Access Article
  • Abstract Page
  • Full-Text
  
  3 - Effect of probiotic supplementation with aerobic training on hepatic IL-6 gene expression in non-alcoholic fatty liver rats
  Masoumeh Hosseini Zahra  Tootoonchi
  Background: non-alcoholic fatty liver disease NAFLD is the most common liver disease in the world, the most important cause of non-alcoholic fatty liver disease is poor eating habits and sedentary lifestyles that cause obesity. The aim of this study was the effect of ae More

  Background: non-alcoholic fatty liver disease NAFLD is the most common liver disease in the world, the most important cause of non-alcoholic fatty liver disease is poor eating habits and sedentary lifestyles that cause obesity. The aim of this study was the effect of aerobic training and probiotic consumption on gene expression of IL6 liver tissue in rats with non-alcoholic fatty liver. Materials and Methods: In this experimental study, 32 male Wistar rats, 200-250 gr, were randomly divided into 4 groups: healthy group, modeled group (steatosis), steatosis + probiotic group, steatosis + probiotic + training group. To create a fatty liver model, tetracycline at a dose of 100 mg / kg at a volume of 1.5 cc per rat was gavaged daily for two weeks. The main training program was for eight weeks/3times per week. In the first week with a speed of 18 meters per minute, the time started 10 minutes and every week quickly, 1-2 meters per minute and time was added to 10 minutes so that in the fourth week the speed to 22 meters per minute and time to 40 minute has arrived. Probiotic groups received 109 CFU / ml of Lactobacillus ramensus by gavage daily for 8 weeks and 5 days a week. 48 hours after the last training session, 10 ml of blood was taken directly from the hearts of rat to test for total cholesterol (TC) and liver tissue samples were taken to test for IL6 gene expression. One-way analysis of variance and Tukey post hoc test was used P≤0.05. Results: There is a significant difference between the IL-6 gene variable in the groups (P=0/000), Induction of fatty liver in rats was associated with a significant increase in interleukin-6 gene levels, these changes were significantly reduced after taking probiotics (P=0/000), Also probiotic consumption with aerobic training had a significant reduction compared to other groups. However taking probiotic with aerobic training had no significant effect on TC of rats with non-alcoholic fatty liver (P=0/306). Conclusion: Probably, performing aerobic training along with taking probiotic can have a better effect in controlling non-alcoholic fatty liver disease. Manuscript profile
• Open Access Article
  • Abstract Page
  • Full-Text
  
  4 - The effect of endurance training and probiotic consumption on IL-18 gene expression in male rats with steatosis
  Valiollah  Shahedi Naghmeh   Tourani Ayub  Kobari
  Background: Fatty liver disease is the most important reason for chronic liver diseases such as liver fibrosis, cirrhosis and liver cancer. The aim of this study was the effect of endurance training and probiotic consumption on IL-18 gene expression in male rats with st More

  Background: Fatty liver disease is the most important reason for chronic liver diseases such as liver fibrosis, cirrhosis and liver cancer. The aim of this study was the effect of endurance training and probiotic consumption on IL-18 gene expression in male rats with steatosis. Materials and Methods: In this experimental study, 32 rats (average weight 200-250 grams) were randomly divided into four groups (healthy control, modeled (steatosis) group, steatosis + probiotic group, and steatosis + probiotic + exercise group). Training groups for 8 weeks, 5 sessions every week, in the beginning week with a speed of 18 meters per minute, time of 10 minutes, and every week the speed of 1-2 meters per minute and the time was increased by 10 minutes, so that In the fourth week, the speed reached 22 meters per minute and the time reached 40 minutes. The groups receiving the supplement received 109 CFU/ml of Lactobacillus rhamnus GG by gavage daily for 8 weeks and 5 days a week. IL-18 gene expression in liver tissue was measured by Real-time PCR method. The data were evaluated using the statistical method of one-way analysis of variance and significance level (P ≥ 0.05). Results: The results showed that endurance training along with probiotic consumption significantly decreased IL-18 gene expression in rats with steatosis. Conclusion: It seems that performing endurance training along with probiotic consumption can have a greater effect than the effect of probiotic alone on IL-18 gene expression. Manuscript profile