Background: Concurrent exercises are one of the most practical exercises for the development of physical fitness factors. Therefore, the aim of this study was to investigate the effect of Concurrent training with calorie Aerobic on suppressing hormones of appetite (leptin, YY peptide and insulin) in overweight women. Materials and Methods: The present study is quasi-experimental research with pre-test-posttest design. In this Study, 30 overweight women (with a BMI> 25), eligible subjects were selected and randomly divided into 2 groups of 15, including the concurrent exercise group and aerobic exercise group. The training protocol in this study was performed for 8 weeks and 3 sessions per week, the duration of each session was 90 minutes and one day in between. Data were evaluated using the statistical method of analysis of covariance at a significant level (P <0.05). Results: The results showed that there was a significant difference between the pre-test and post-test variables of fat percentage, leptin hormone, insulin hormone, maximum oxygen consumption, BMI, muscle endurance in concurrent exercise group with calorie Aerobic and aerobic exercise group (P <0.05). Conclusion: The results of this study show that doing concurrent exercises with calorie Aerobic in overweight women reduces weight and improves appetite-related hormones. Manuscript profile