The role of phenotypic, genotypic and drug resistance characteristics of Morganella morganii in pathogenicity and nosocomial infections
Subject Areas : Antimicrobial compoundsErfan Shahbazi 1 , Hamidreza Mollasalehi 2 , Darush Minai-Tehrani 3
1 - 1. Faculty of biological sciences and technology, Shahid Beheshti university, Tehram, Iran
2 - Protein Research Center, Shahid Beheshti University, Tehram, Iran
3 - Faculty of biological sciences and technology, Shahid Beheshti university, Tehram, Iran
Keywords: Morganella morganii, opportunistic pathogen, Pathogenicity, Antibiotic resistant.,
Abstract :
Aim and background: The gram negative facultative anaerobic bacilli Morganella morganii is mostly found in the environment and also human, reptile and mammals’ intestinal tracts as a part of normal flora. M. morganii is mostly considered as an opportunistic pathogen which mostly causes nosocomial infections. Regarding the capability of this bacterium in carrying different drug resistance genes in its genome, M. morganii is challenging the clinical infection control. Furthermore M. morganii is considered as an important pathogen due to the virulence evolution. Peritonitis, pneumonia, empyema, arthropathy, pericarditis, endophethalmitis, meningitis, wound infection and bacteremia are the infections which can occur because of M. morganii. Results: Accumulated data has shown that M. morganii often causes a high percentage of mortality in patients who suffer from some infections. However, this bacterium has been neglected in the word and especially in our country. Discussion: This study aims to review the phenotypic and genotypic features of M. morganii and the role of these attributes in the pathogenicity of this bacterium. This information can be used to find a rapid and efficient way to detect and opt for the best way of prevention and treatment of M. morganii.
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