اثربخشی تحریک جریان مستقیم فراجمجمه‌ای (tDCS) بر عملکرد حافظه کاری در افراد سالم
الموضوعات :نیما گنجی 1 , رزا راشدی 2 , نگار کریمی 3 , پروانه فرهاد بیگی 4 , علی اکبر سلیمانی 5 , اعظم نوفرستی 6 , محمد حسین عبدالهی 7 , فاطمه معین الغربایی 8
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الکلمات المفتاحية: حافظه کاری, تحریک الکتریکی مستقیم فراجمجمه ای (tDCS), قشر پیش‌پیشانی خلفی‌جانبی (DLPFC),
ملخص المقالة :
مقدمه: حافظه کاری یکی از توانمندی‌های شناختی بنیادین است که ما را در انجام پردازش‌های ذهنی پیچیده یاری می‌‌کند اما دارای ظرفیت محدودی است. دانشمندان در پی راه‌کارهایی جهت بالابردن ظرفیت حافظه کاری هستند. مطالعات فراوانی تأثیر تحریک مستقیم فراجمجمه‌ای (tDCS) را بر جنبه‌های مختلف عملکرد نشان داده است. هدف از این پژوهش بررسی اثربخشی تحریک جریان مستقیم فراجمجمه‌ای بر عملکرد حافظه کاری در افراد سالم است. روش: در این مطالعه به‌طور مشخص تأثیر دوره تحریک سه جلسه‌ای tDCS آندی با شدت 2 میلی‌آمپر در ناحیه قشر پیش‌پیشانی خلفی جانبی بر روی عملکرد حافظه کاری افراد سالم در دو گروه تصادفی آزمایشی و گواه با استفاده از آزمون n-back موردبررسی قرار گرفت. یافته‌ها: نتایج حاکی از آن بود که آزمودنی‌ها پس از سه جلسه تحریک مستقیم فراجمجمه‌ای، نسبت به قبل از مداخله تعداد پاسخ‌های درست‌تری (00/0P=) را در زمان کمتر (00/0P=) در آزمون n-back ارائه دادند. آزمودنی ها در گروه گواه که تحریک شم را دریافت کردند، تفاوت معناداری در نتایج نشان ندادند. نتیجه‌گیری: معناداری نتایج در آزمون n-back قبل و بعد از مداخله tDCS، نشان می‌دهد تحریک فراجمجمه‌ای آندی بر روی قشر پیش‌پیشانی خلفی‌جانبی موجب بهبود عملکرد حافظه کاری در آزمودنی‌های سالم می‌گردد.
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