مروري بر الاستومرهاي زيست تخريب پذير: سنتز، پيشرفت ها و کاربردهاي زيست پزشکي
الموضوعات :محمدحسین احمدی 1 , جعفر خادم زاده يگانه 2
1 - قم، دانشگاه صنعتي قم، دانشکده فني و مهندسي، گروه مهندسی پليمر
2 - دانشگاه صنعتی قم
الکلمات المفتاحية: الاستومر, زیست تخریب پذیر, پلي استر, پلي اورتان, زيست‌پزشکي.,
ملخص المقالة :
الاستومرهاي زيست تخريب پذير مصنوعي، مانند پلي استرها و پلي يورتان ها، استراتژي ها و ابزارهاي درماني زيست پزشکي را متحول نموده اند. با کمک نوآوري در سنتز و فن آوري هاي فراورش، الاستومرهايي زيست تخريب پذير با خواص قابل کنترل و کارکردهاي مختلف توسعه يافته اند. الاستومرهاي زيست تخريب پذير به دليل قابليت کشساني بالا و استحکام ضربه عالي مي توانند تغيير شکل هاي مکرر را در دماي اتاق يا دماي بدن انسان تحمل و بازيابي کنند. بافت انعطاف پذير و خاصيت ارتجاعي الاستومرهاي زيست تخريب پذير آنها را قادر مي سازد تا خواص مکانيکي بافت هاي نرم بومي در بدن را تقليد کنند و خواص مکانيکي مناسب براي ساختارهاي مهندسي بافت ايجاد کنند. در اين بررسي، پيشرفت‌هاي اخير در سنتز، فناوري‌هاي فرآيند و کاربردهاي زيست‌پزشکي الاستومرهاي زيست تخريب‌پذير که به طور عمده بر پايه پلي استر و پلي اورتان مي باشند، خلاصه شده است. براي برآوردن نيازهاي متنوع کاربردهاي زيست پزشکي، الاستومرهاي زيست تخريب پذير چند منظوره با تنظيم روابط مکانيکي مناسب و رفتارهاي زيست تخريب پذير، بهبود زيست سازگاري و زيست فعالي و همچنين ساخت عملکردهاي هوشمند در حال توسعه هستند. سپس، کاربرد الاستومرهاي زيست تخريب پذير در زمينه مهندسي قلب و عروق، عصب و بافت استخوان، چسب زيستي مرور مي گردد. با وجود پیشرفت قابل توجه، هنوز بین مواد مورد نظر بالینی و الاستومرهای زیست تخریب پذیر گزارش شده از نظر خواص مکانیکی پیچیده و عملکردهای متنوع فاصله وجود دارد.
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