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دسترسی آزاد مقاله
1 - Chronic L-Carnitine Supplementation on Exercise Performance, Blood Lactate, and Exercise-Induced Oxidative Stress in Resistance-Trained Males
Ebrahim FallahBackground: The purpose of the present study is to investigate the effect of Chronic L-Carnitine Supplementation on Exercise Performance, Blood Lactate, and Exercise-Induced Oxidative Stress in Resistance-Trained Males Materials and Methods: We examined 35 resistance-t چکیده کاملBackground: The purpose of the present study is to investigate the effect of Chronic L-Carnitine Supplementation on Exercise Performance, Blood Lactate, and Exercise-Induced Oxidative Stress in Resistance-Trained Males Materials and Methods: We examined 35 resistance-trained (1y) male participants (25±2y, 79.8±8.9 kg, 16.1±5.53% body fat) for 9-wk of L-carnitine supplementation in conjunction with resistance training on exercise performance, blood lactate, and exercise-induced oxidative stress. Randomized, placebo-controlled, double-blind treatment of a (1) no intervention, no supplement Control (CON, n=12), (2) maltodextrose Placebo (PLA, 2 g/d, n=11) or (3) L-carnitine (LCR, 2 g/d, n=12). Exercise performance, post-exercise blood lactate (BL) and oxidative stress markers were analyzed at weeks 3, 6, and 9. The PLA and LCR groups followed a specific resistance training program (4 d/w, upper body/lower body split) for a 9-wk. Data were analyzed by GLM and presented as mean (SD) or change (95% CI). Primary outcomes were total lifting volume for the bench (BP) and leg press (LP). Results: The results a significant increase in BP lifting volume at wk-6 (139 kg, 95% CI 49.1, 230) and wk-9 (238 kg, 95% CI 132, 343) for LCR. Similar results were observed for LP. We also observed a significant increase in Wingate mean power (63.4 W, 95% CI 30.5, 96.3) and peak power (239 W/kg, 95% CI 104, 374) at wk-9 for LCR as well as a significant reduction in post-exercise BL levels and oxidative stress responses. No differences were observed in body composition. Conclusion: These findings indicate that LCR supplementation improves exercise performance and attenuates the blood lactate and oxidative stress response to resistance training. پرونده مقاله -
دسترسی آزاد مقاله
2 - Effect of resistance training and nanocurcumin supplementation on the expression of FNDC5 and PPARƔ genes in rat muscle tissue
Amir Maleki Masoumeh HosseiniBackground: Irisin is released from the Fndc5 protein in muscle cell through physical activity and effects on metabolism through browning of white fat. The purpose of this study was to the effect of resistance training and supplementation of nanocurcumin on the expressi چکیده کاملBackground: Irisin is released from the Fndc5 protein in muscle cell through physical activity and effects on metabolism through browning of white fat. The purpose of this study was to the effect of resistance training and supplementation of nanocurcumin on the expression of genes of FNDC5 and PPARɣ rat muscle tissue. Materials and Methods: In this experimental study, 32 rats were randomly divided into four groups (Control, resistance training, nanocurcumin, resistance training + nanocurcumin). The training groups program included 4 weeks, 3 days a week from climbing on a stepladder. Nanocarcmine (80 mg / kg) was given gavage in complementary groups for four weeks daily. FNDC5 and PPARƔ gene expression were measured using the RT-PCR method. Data were analyzed using one-way ANOVA with a significant level of P≤0.05. Results: The results showed that resistance training and supplementation of Nanocarcmine significantly increased the expression of the gene of FNDC5 and PPARɣ in muscle tissue of rat (P <0.05). Conclusion: It seems resistance training with nanocurcumin supplementation may stimulate secretion of FNDC5 & PPARƔ from muscle, that has a key role in the metabolism of adipose tissue and the conversion of white tissue to brown fat tissue. پرونده مقاله -
دسترسی آزاد مقاله
3 - Influence of Β-Hydroxy-Β-Methyl Butyrate Supplementation on Strength, Muscle and Liver-Damage Indices Induced by Dual Pyramid Resistance Training in Beginner Bodybuilders
Soleyman Ansari Shahram Gholamrezaei Fahimeh AdibSaber Mohammad MoradniaBackground: It has been suggested that ingesting supplements decrease muscle soreness, increase muscle strength, hypertrophy, and health-related indices. This study investigated the influence of 8-week β-Hydroxy-β-Methyl butyrate (HMB) supplementation combined with a du چکیده کاملBackground: It has been suggested that ingesting supplements decrease muscle soreness, increase muscle strength, hypertrophy, and health-related indices. This study investigated the influence of 8-week β-Hydroxy-β-Methyl butyrate (HMB) supplementation combined with a dual pyramid resistance exercise program on strength, muscle, and liver-damage indices (ALT, AST, CK, and LDH) and body mass index (BMI) in beginner bodybuilders. Materials and Methods: A total of 40 beginner bodybuilders was randomized to an intervention group (resistance training + HMB supplementation) and a control group (resistance training + placebo) for 8 weeks. Blood samples and body measurements were taken at baseline and after the end of the intervention. The subjects were evaluated for BMI, 1 repetition maximum (1RM) bench press and leg press prior to and after the training intervention. In addition, blood samples were obtained before and after 8-week resistance training to evaluate creatine kinase (CK), lactate dehydrogenase (LD), aspartate aminotransferase (AST), and alanine aminotransferase (Johnson et al.) responses. Results: After 8 weeks of HMB ingestion, serum levels of CK (p<0.001), LDH (p<0.014), and ALT (p<0.009) of participants in the experimental group significantly decreased compared to the placebo group. Furthermore, The HMB group showed greater gains compared with the placebo group in 1RM leg and bench press (p<0.001). Regarding BMI and AST serum levels, there were no significant differences between groups. Conclusion: The results of the present study showed that HMB supplementation may attenuate the resistance exercise-induced muscle and liver damage indices and have beneficial effects on muscle strength. پرونده مقاله -
دسترسی آزاد مقاله
4 - Effect of 8-week metabolic resistance training and Chlorogenic acid supplement on the expression of UCP1: A randomized clinical trial
Maryam Takhty Farshad Ghazalian Shahram Soheili khosrow EbrahimBackground: Obesity and overweight is one of the major public health challenges all around the world. The aim of this study was to evaluate the simultaneous effect of eight weeks of metabolic resistance training (MRT) and Chlorogenic Acid (CGA) supplementation on weight چکیده کاملBackground: Obesity and overweight is one of the major public health challenges all around the world. The aim of this study was to evaluate the simultaneous effect of eight weeks of metabolic resistance training (MRT) and Chlorogenic Acid (CGA) supplementation on weight loss, expression level of UCP1in overweight women. Materials and Methods: The present study was a randomized clinical trial performed in 2022 on a sample of overweight women in Iran. Participants in the study were randomly divided into four groups including combined 8-week course of MRT training and CGA supplementation, 8-week course of MRT, CGA supplement, and the control group. Intervention included three training sessions per week and the duration of each session was 45 minutes. The supplementation arms were also received 400 mg / day CGA extracted from green coffee beans. Expression level of Uncoupling Protein 1 (UCP1) was the main interested outcome that assessed pre and post intervention. Results: In the MRT exercise group, UCP1 expression increased by 4.3 units on average over the 8-week intervention. The highest increase was observed in participants who received both CGA supplement and MRT exercise where UCP1 increased from 22.5 (1.2) to 28.0 (3.5) over the study period (P<0.05). No significant increase was observed in CGA supplementation group. Conclusion: MRT exercises with and without CGA supplementation stimulated expression level of UCP1 mRNA. پرونده مقاله -
دسترسی آزاد مقاله
5 - Effect of 8-week simultaneous metabolic resistance training and Chlorogenic acid supplement on the expression level of BMP2, BMP4, BMP6, and BMP7: A randomized open label clinical trial
Maryam Takhty Farshad Ghazalian Shahram Soheili khosrow EbrahimBackground: BMP has critical role in development, growth, and differentiation of cell. There is enough evidence regarding the role of BMPs in lipid accumulation and homeostasis The current study aimed to evaluate the simultaneous effect of eight weeks of metabolic resis چکیده کاملBackground: BMP has critical role in development, growth, and differentiation of cell. There is enough evidence regarding the role of BMPs in lipid accumulation and homeostasis The current study aimed to evaluate the simultaneous effect of eight weeks of metabolic resistance training (MRT) and Chlorogenic Acid (CGA) supplementation on expression level of BMP2, BMP4, BMP6, and BMP7 in overweight women. Materials and Methods: We carried-out a randomized clinical trial performed on 40 overweight women in Iran 2020. We randomly assigned the study participants into four groups including combined 8-week course of metabolic resistance training (MRT) training and 400 mg chlorogenic acid (CGA) supplementation, 8-week course of MRT, CGA supplement, and the control group. Intervention included three MRT training sessions per week and the duration of each session was 45 minutes. The training exercise intervention was 10 minutes of warm-up, 30 minutes of metabolic resistance training, and 5 minutes of cool-down. The supplementation arms were also received 400 mg / day CGA extracted from green coffee beans. Expression level of BMP2,4,6, and 7 was the main interested outcome that assessed pre and post intervention. Results: We observed significant decrease in BMP2 level in combined intervention group in compared with the control group (Regression coefficient= -2.7, 95% CI=-5.0, -0.4). Moreover, we observed that combined intervention has decreased BMP4 level and the observed difference was statistically significant (Regression coefficient= -6.2, -1.7, -10.6). No significant effect for MRT and CGA group was reported regarding BMP2, and BMP4. Neither combined nor separate form of CGA and MRT had no significant effect on BMP6 and BMP7 (P-value>0.05). Conclusion: Simultaneous MRT exercises and CGA supplementation prohibited expression levels of BMP2, and BMP4. However, they had no significant effect separately. There was no association between the interventions and expression level of BMP6, and BMP7. Abstract Background and Objective: BMP has critical role in development, growth, and differentiation of cell. There is enough evidence regarding the role of BMPs in lipid accumulation and homeostasis The current study aimed to evaluate the simultaneous effect of eight weeks of metabolic resistance training (MRT) and Chlorogenic Acid (CGA) supplementation on expression level of BMP2, BMP4, BMP6, and BMP7 in overweight women. Material and methods: We carried-out a randomized clinical trial performed on 40 overweight women in Iran 2020. We randomly assigned the study participants into four groups including combined 8-week course of metabolic resistance training (MRT) training and 400 mg chlorogenic acid (CGA) supplementation, 8-week course of MRT, CGA supplement, and the control group. Intervention included three MRT training sessions per week and the duration of each session was 45 minutes. The training exercise intervention was 10 minutes of warm-up, 30 minutes of metabolic resistance training, and 5 minutes of cool-down. The supplementation arms were also received 400 mg / day CGA extracted from green coffee beans. Expression level of BMP2,4,6, and 7 was the main interested outcome that assessed pre and post intervention. Results: We observed significant decrease in BMP2 level in combined intervention group in compared with the control group (Regression coefficient= -2.7, 95% CI=-5.0, -0.4). Moreover, we observed that combined intervention has decreased BMP4 level and the observed difference was statistically significant (Regression coefficient= -6.2, -1.7, -10.6). No significant effect for MRT and CGA group was reported regarding BMP2, and BMP4. Neither combined nor separate form of CGA and MRT had no significant effect on BMP6 and BMP7 (P-value>0.05). Conclusion: Simultaneous MRT exercises and CGA supplementation prohibited expression levels of BMP2, and BMP4. However, they had no significant effect separately. There was no association between the interventions and expression level of BMP6, and BMP7. پرونده مقاله
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