• List of Articles peptide

      • Open Access Article

        1 - Biomarkers of myocardial and skeletal muscle diseases in small animals
        Maedeh Ghari Mahdieh  Zaeemi
        Muscle diseases can be either inherited or acquired that result from several different disease processes including; infectious, drug- and toxin-induced, and immune mediated, endocrine and metabolic disorders. Standard hematological and biochemical, immunologic, molecula More
        Muscle diseases can be either inherited or acquired that result from several different disease processes including; infectious, drug- and toxin-induced, and immune mediated, endocrine and metabolic disorders. Standard hematological and biochemical, immunologic, molecular, pathological tests are indicated to diagnosis and monitoring these diseases. From the biochemical tests, the serum activities of aspartate aminotransferase enzymes, lactate dehydrogenase, creatinine kinase, and serum concentration of lactate, myoglobin, troponins, natriuretic peptides, are measured. The aim of this study is to introduce biomarkers that used nowadays to detect skeletal muscle and myocardial damage in small animals. It also provides information on the structure, function, metabolism, reference values and applicability of these biomarkers to provide a better understanding of the health status of skeletal and myocardial muscles by choosing an appropriate biomarker. Manuscript profile
      • Open Access Article

        2 - Concurrent Exercise Training on Appetite Suppressant Hormones in Overweight Women
        Maryam Takhty Asal  Ziloubaf Samira  Feridoni Sadra   Sheidaei Mostafa Rahimi
        Background: Concurrent exercises are one of the most practical exercises for the development of physical fitness factors. Therefore, the aim of this study was to investigate the effect of Concurrent training with calorie Aerobic on suppressing hormones of appetite (lept More
        Background: Concurrent exercises are one of the most practical exercises for the development of physical fitness factors. Therefore, the aim of this study was to investigate the effect of Concurrent training with calorie Aerobic on suppressing hormones of appetite (leptin, YY peptide and insulin) in overweight women. Materials and Methods: The present study is quasi-experimental research with pre-test-posttest design. In this Study, 30 overweight women (with a BMI> 25), eligible subjects were selected and randomly divided into 2 groups of 15, including the concurrent exercise group and aerobic exercise group. The training protocol in this study was performed for 8 weeks and 3 sessions per week, the duration of each session was 90 minutes and one day in between. Data were evaluated using the statistical method of analysis of covariance at a significant level (P <0.05). Results: The results showed that there was a significant difference between the pre-test and post-test variables of fat percentage, leptin hormone, insulin hormone, maximum oxygen consumption, BMI, muscle endurance in concurrent exercise group with calorie Aerobic and aerobic exercise group (P <0.05). Conclusion: The results of this study show that doing concurrent exercises with calorie Aerobic in overweight women reduces weight and improves appetite-related hormones. Manuscript profile
      • Open Access Article

        3 - Self-Assembly of Peptides and its Applications: A Review
        Soheila Emamyari
        Molecular self-assembly is the spontaneous aggregation of molecules or macromolecules into supramolecular structures with non-covalent interactions. This phenomenon is an interdisciplinary research topic that has a lot of potential applications in various fields. One of More
        Molecular self-assembly is the spontaneous aggregation of molecules or macromolecules into supramolecular structures with non-covalent interactions. This phenomenon is an interdisciplinary research topic that has a lot of potential applications in various fields. One of the main driving forces of molecular self-assembly is the existence of molecular amphiphilicity in the system which can cause microphase separation and create complex and stable nanostructures. Self-assembling peptides are one of the most important classes of molecules with the ability to self-assemble. The rich self-assembly behavior is observed in systems of peptides, due to the simultaneous presence of different interactions (such as electrostatic interaction, hydrophobicity and hydrogen bond) in systems consisting of them and the diversity of their molecular configuration. Better understanding of peptides self-assembly enables the better design of peptides to form functional nanostructures. In this review article, at first, peptide self-assembly and its importance are stated. Then, some examples of self-assembling peptides which have attracted the interest of scientists for various reasons, such as cyclic peptides, amphiphilic peptides, ionic complementary peptides and some other examples, are explained. Also, some important applications and benefits of peptides self-assembly, which include nanoscale construction, tissue engineering, drug delivery, applications in biosensors, and the study of conformational diseases, are reviewed. Manuscript profile