List of Articles obese and overweight women

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  1 - Effect of 8-week metabolic resistance training and Chlorogenic acid supplement on the expression of UCP1: A randomized clinical trial
  Maryam Takhty Farshad   Ghazalian Shahram  Soheili khosrow  Ebrahim
  10.52547/jspac.40308.3.7.50
  Background: Obesity and overweight is one of the major public health challenges all around the world. The aim of this study was to evaluate the simultaneous effect of eight weeks of metabolic resistance training (MRT) and Chlorogenic Acid (CGA) supplementation on weight More

  Background: Obesity and overweight is one of the major public health challenges all around the world. The aim of this study was to evaluate the simultaneous effect of eight weeks of metabolic resistance training (MRT) and Chlorogenic Acid (CGA) supplementation on weight loss, expression level of UCP1in overweight women. Materials and Methods: The present study was a randomized clinical trial performed in 2022 on a sample of overweight women in Iran. Participants in the study were randomly divided into four groups including combined 8-week course of MRT training and CGA supplementation, 8-week course of MRT, CGA supplement, and the control group. Intervention included three training sessions per week and the duration of each session was 45 minutes. The supplementation arms were also received 400 mg / day CGA extracted from green coffee beans. Expression level of Uncoupling Protein 1 (UCP1) was the main interested outcome that assessed pre and post intervention. Results: In the MRT exercise group, UCP1 expression increased by 4.3 units on average over the 8-week intervention. The highest increase was observed in participants who received both CGA supplement and MRT exercise where UCP1 increased from 22.5 (1.2) to 28.0 (3.5) over the study period (P<0.05). No significant increase was observed in CGA supplementation group. Conclusion: MRT exercises with and without CGA supplementation stimulated expression level of UCP1 mRNA. Manuscript profile
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  2 - Effect of 8-week simultaneous metabolic resistance training and Chlorogenic acid supplement on the expression level of BMP2, BMP4, BMP6, and BMP7: A randomized open label clinical trial
  Maryam Takhty Farshad  Ghazalian Shahram   Soheili khosrow   Ebrahim
  Background: BMP has critical role in development, growth, and differentiation of cell. There is enough evidence regarding the role of BMPs in lipid accumulation and homeostasis The current study aimed to evaluate the simultaneous effect of eight weeks of metabolic resis More

  Background: BMP has critical role in development, growth, and differentiation of cell. There is enough evidence regarding the role of BMPs in lipid accumulation and homeostasis The current study aimed to evaluate the simultaneous effect of eight weeks of metabolic resistance training (MRT) and Chlorogenic Acid (CGA) supplementation on expression level of BMP2, BMP4, BMP6, and BMP7 in overweight women. Materials and Methods: We carried-out a randomized clinical trial performed on 40 overweight women in Iran 2020. We randomly assigned the study participants into four groups including combined 8-week course of metabolic resistance training (MRT) training and 400 mg chlorogenic acid (CGA) supplementation, 8-week course of MRT, CGA supplement, and the control group. Intervention included three MRT training sessions per week and the duration of each session was 45 minutes. The training exercise intervention was 10 minutes of warm-up, 30 minutes of metabolic resistance training, and 5 minutes of cool-down. The supplementation arms were also received 400 mg / day CGA extracted from green coffee beans. Expression level of BMP2,4,6, and 7 was the main interested outcome that assessed pre and post intervention. Results: We observed significant decrease in BMP2 level in combined intervention group in compared with the control group (Regression coefficient= -2.7, 95% CI=-5.0, -0.4). Moreover, we observed that combined intervention has decreased BMP4 level and the observed difference was statistically significant (Regression coefficient= -6.2, -1.7, -10.6). No significant effect for MRT and CGA group was reported regarding BMP2, and BMP4. Neither combined nor separate form of CGA and MRT had no significant effect on BMP6 and BMP7 (P-value>0.05). Conclusion: Simultaneous MRT exercises and CGA supplementation prohibited expression levels of BMP2, and BMP4. However, they had no significant effect separately. There was no association between the interventions and expression level of BMP6, and BMP7. Abstract Background and Objective: BMP has critical role in development, growth, and differentiation of cell. There is enough evidence regarding the role of BMPs in lipid accumulation and homeostasis The current study aimed to evaluate the simultaneous effect of eight weeks of metabolic resistance training (MRT) and Chlorogenic Acid (CGA) supplementation on expression level of BMP2, BMP4, BMP6, and BMP7 in overweight women. Material and methods: We carried-out a randomized clinical trial performed on 40 overweight women in Iran 2020. We randomly assigned the study participants into four groups including combined 8-week course of metabolic resistance training (MRT) training and 400 mg chlorogenic acid (CGA) supplementation, 8-week course of MRT, CGA supplement, and the control group. Intervention included three MRT training sessions per week and the duration of each session was 45 minutes. The training exercise intervention was 10 minutes of warm-up, 30 minutes of metabolic resistance training, and 5 minutes of cool-down. The supplementation arms were also received 400 mg / day CGA extracted from green coffee beans. Expression level of BMP2,4,6, and 7 was the main interested outcome that assessed pre and post intervention. Results: We observed significant decrease in BMP2 level in combined intervention group in compared with the control group (Regression coefficient= -2.7, 95% CI=-5.0, -0.4). Moreover, we observed that combined intervention has decreased BMP4 level and the observed difference was statistically significant (Regression coefficient= -6.2, -1.7, -10.6). No significant effect for MRT and CGA group was reported regarding BMP2, and BMP4. Neither combined nor separate form of CGA and MRT had no significant effect on BMP6 and BMP7 (P-value>0.05). Conclusion: Simultaneous MRT exercises and CGA supplementation prohibited expression levels of BMP2, and BMP4. However, they had no significant effect separately. There was no association between the interventions and expression level of BMP6, and BMP7. Manuscript profile