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      • Open Access Article

        1 - Breast Cancer Classification Approaches - A Comparative Analysis
        Mohan Kumar Sunil Kumar Khatri Masoud Mohammadian
        Cancer of the breast is a difficult disease to treat since it weakens the patient's immune system. Particular interest has lately been shown in the identification of particular immune signals for a variety of malignancies in this regard. In recent years, several methods More
        Cancer of the breast is a difficult disease to treat since it weakens the patient's immune system. Particular interest has lately been shown in the identification of particular immune signals for a variety of malignancies in this regard. In recent years, several methods for predicting cancer based on proteomic datasets and peptides have been published. The cells turns into cancerous cells because of various reasons and get spread very quickly while detrimental to normal cells. In this regard, identifying specific immunity signs for a range of cancers has recently gained a lot of interest. Accurately categorizing and compartmentalizing the breast cancer subtype is a vital job. Computerized systems built on artificial intelligence can substantially save time and reduce inaccuracy. Several strategies for predicting cancer utilizing proteomic datasets and peptides have been reported in the literature in recent years.It is critical to classify and categorize breast cancer treatments correctly. It's possible to save time while simultaneously minimizing the likelihood of mistakes using machine learning and artificial intelligence approaches. Using the Wisconsin Breast Cancer Diagnostic dataset, this study evaluates the performance of various classification methods, including SVC, ETC, KNN, LR, and RF (random forest). Breast cancer can be detected and diagnosed using a variety of measurements of data (which are discussed in detail in the article) (WBCD). The goal is to determine how well each algorithm performs in terms of precision, recall, and accuracy. The variation of each classification threshold has been tested on various algorithms and SVM turned out to be very promising. Manuscript profile
      • Open Access Article

        2 - Identification of Cancer-Causing Genes in Gene Network Using Feedforward Neural Network Architecture
        مصطفی اخوان صفار abbas ali rezaee
        Identifying the genes that initiate cancer or the cause of cancer is one of the important research topics in the field of oncology and bioinformatics. After the mutation occurs in the cancer-causing genes, they transfer it to other genes through protein-protein interact More
        Identifying the genes that initiate cancer or the cause of cancer is one of the important research topics in the field of oncology and bioinformatics. After the mutation occurs in the cancer-causing genes, they transfer it to other genes through protein-protein interactions, and in this way, they cause cell dysfunction and the occurrence of disease and cancer. So far, various methods have been proposed to predict and classify cancer-causing genes. These methods mostly rely on genomic and transcriptomic data. Therefore, they have a low harmonic mean in the results. Research in this field continues to improve the accuracy of the results. Therefore, network-based methods and bioinformatics have come to the aid of this field. In this study, we proposed an approach that does not rely on mutation data and uses network methods for feature extraction and feedforward three-layer neural network for gene classification. For this purpose, the breast cancer transcriptional regulatory network was first constructed. Then, the different features of each gene were extracted as vectors. Finally, the obtained vectors were given to a feedforward neural network for classification. The obtained results show that the use of methods based on multilayer neural networks can improve the accuracy and harmonic mean and improve the performance compared to other computational methods. Manuscript profile