List of Articles Cox

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  1 - Study of the city in political geography and geopolitical with an emphasis on Gottman and Cox's theory
  hassan kamran   yashar zaki    
  "City" is not only a political-spatial phenomenon, but also a geopolitical phenomenon which is the basis for the achievement of national power. Due to its specific characteristics, the city is the main place to meet the mental, intellectual and physical needs of human b More

  "City" is not only a political-spatial phenomenon, but also a geopolitical phenomenon which is the basis for the achievement of national power. Due to its specific characteristics, the city is the main place to meet the mental, intellectual and physical needs of human beings in every country. Therefore, it can be said that cities and towns are responsible for maintaining the financial and material resources of the country. Cities on a global scale are powerful political spaces that enter the process of competition and interaction by controlling local events at the regional and global levels. Hence, the dramatic growth of large cities suggests that the state has provided a model for the development of the future of political geography. In other words, As the population increases The transformation of many non-urban spaces into urban space As well as by designing new patterns and working strategies for organizing urban space And the increasing political and strategic role of cities can be acknowledged Which has become the focal point of studies in geopolitical and geopolitical geography But how this phenomenon is studied from the perspective of geo-political geopolitics and geopolitics, The question that the present paper deals with The results of this research by analytical-descriptive method show that The phenomenon of the city has been studied not only in one dimension, but also in multidimensional forms, both theoretical and applied by geographers and geopolitics Manuscript profile
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  2 - The effect of exercise and vitamin B6 on the expression of COX2 and IL-1B genes in endometrial tissue of endometriosis rats
  Fatemeh Rashidpour Parvin  Farzanegi Hajar   Abbaszadeh
  10.61186/jspac.39258.2.6.31
  Background: Endometriosis is a chronic disease, afflicting about 5-10% of women. Many possible environmental and molecular factors have been proposed for the pathogenesis of endometriosis; nevertheless, its real mechanism is still under investigation. This research aime More

  Background: Endometriosis is a chronic disease, afflicting about 5-10% of women. Many possible environmental and molecular factors have been proposed for the pathogenesis of endometriosis; nevertheless, its real mechanism is still under investigation. This research aimed to examine the effect of physical exercise and B6 vitamin on the expression of COX2 and IL-1B genes on endometriotic tissue in endometriosis model rats. Materials and Methods: In this experimental research, 25 Wistar rats were randomly assigned into five groups: control-healthy, endometriosis, endometriosis + exercise, endometriosis + B6, endometriosis + exercise + B6. Vitamin B6 were administered as 60 mg/kg per body weight of each rat. The swimming exercise program involved 8 weeks of exercise, each week 5 days, and each day for 30 min. For data analysis, one-way analysis of variance (ANOVA) and post hoc Tukey test were used. Results: The extent of expression of COX and IL-1β genes increased significantly in the endometriosis group compared to the control-healthy group. All three groups of endometriosis + exercise, endometriosis + B6, and endometriosis + exercise + B6 showed a significant reduction of COX2 expression compared to the endometriosis group. Two groups of endometriosis + exercise and endometriosis + exercise + B6 indicated a significant decline in the extent of expression of 1L-1β gene, as compared to the endometriosis group. The endometriosis + exercise + B6 group revealed a significant reduction in the extent of expression of COX2 and IL-1β genes compared to endometriosis + B6. Finally, the endometriosis + exercise group revealed a significant decrease in the extent of expression of IL-1β gene, when compared with the endometriosis + B6. Conclusion: Overall, the results suggest that changes in the key molecules or signaling pathways as well as gene expression in the endometriosis process can contribute to improving this condition. Doing physical activity and concurrent consumption of B6 vitamin will be helpful in curbing this disease and improving the level of this condition. Manuscript profile