Studing Antimicrobial effects of Prodigiosin pigment from Serratia marcescens bacteria against bacteria causing urinary tract infections
Subject Areas : Antimicrobial compoundsFaeezeh Bahrami 1 , Farzaneh Farzaneh 2 , Abbas Akhavan sepahi 3
1 - Department of Microbiology, Islamic Azad University, Tehran North Branch, Tehran, Iran,
2 - Department of Microbiology, Islamic Azad University, Tehran North Branch, Tehran, Iran,
3 - Department of Microbiology, Islamic Azad University, Tehran North Branch, Tehran, Iran,
Keywords: Serratia marcescens, Prodigiosin, Urinary Tract Infection,
Abstract :
Aim and Background: Today, more opportunistic human pathogens, including bacteria that cause urinary tract infections, are more resistant to a wide range of antibiotics, it making more difficult to treat them. Materials and Methods: In this study, Prodigiosin pigment was extracted from Serratia marcescens bacteria and its antimicrobial effect was evaluated on a number of urinary tract bacteria collected from Tehran's medical diagnostic laboratories. Results: The results of this study showed that this pigment has been most diameter of inhibition zone for Staphylococcus saprophyticus and then the genus Enterococcus in every three methods of disc diffusion test, well diffusion and MIC. Discussion: This study showed that with due attention to the antimicrobial effect of Prodigiosin pigment, this microbial pigment could be a good alternative to chemical drugs in the future. Conclusion: The results obtained in this study showed that Prodigiosin pigment has antimicrobial effect on gram positive bacteria more than gram negative bacteria.
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