نگاهی تازه به آخرین روش های درمانی ترمیمی و مکمل در آسیب های اندام حرکتی اسب های ورزشی: با تاکید بر ضایعات بافت نرم
الموضوعات :
امیر زکیان
1
(دانشگاه لرستان)
فرشید داوودی
2
(دستیار جراحی دامپزشکی، گروه جراحی و تصویربرداری تشخیصی، دانشکده دامپزشکی، دانشگاه ارومیه، ارومیه، ایران.)
الکلمات المفتاحية: طب ورزشی, طب مکمل, طب جایگزین, اندام حرکتی,
ملخص المقالة :
امروزه با توجه به فشردگی بالای مسابقات ورزشی و بروز آسیب های بیشتر، نقش طب ورزشی در به حداقل رساندن طول دوره درمان و برگشت دام به عملکرد قبلی با حداکثر توان پر رنگ تر از قبل شده است. روش های درمانی غیر رایجی برای این امر به کار بسته می شود، اما مورد پذیرش همه پزشکان و دامپزشکان در سراسر دنیا نمیباشد. باید طب مکمل یا جایگزین را نوعی روش درمانی دانست که در دنیای پزشکی امروز قرار ندارد و یا حتی ثبت نشده است، اما برخی از افراد و جوامع از آن به عنوان بهترین روش درمانی یاد می‌کنند و برای آن شاخه‌ها و زیر مجموعه‌هایی حرفه ای تعریف می‌نمایند. اما شاخه غیر مرسوم دیگری جهت درمان بیماری ها طب ترمیمی یا بازساختی است. در سال های اخیر، پیشرفت هایی در بیولوژی سلولی، ایمونولوژی ژنتیک و رشته های دیگر، موجب شده پزشکی ترمیمی بتواند مراقبت های بهداشتی را به طور اساسی تغییر دهد. از جمله وظایف سازمانهای دولتی و بین المللی که در امر بهداشت و درمان فعالیت دارند این است که اطلاع رسانی درست و آگاهی بخشی مناسبی نسبت به تمام رشته های طب مکمل و ترمیمی برای درمانگران و مالکین اسب-ها ایجاد کنند تا هر فرد پس از بررسی و مشاوره گرفتن، به فراخور نیاز و مشکلات خود از این شاخه های طب استفاده کند. در سالیان اخیر پیشرفت-های شگرفی در زمینه این دو شاخه طب غیر مرسوم در کشورهای اروپایی و آمریکای شمالی در سطح آکادمیک و مجامع علمی دامپزشکی به خصوص در شاخه طب ورزشی ایجاد شده است
1. Hinchliff KW, Kaneps AJ, Geor R. Equine sport medicine and surgery. 2nd edition, Elsevier Saunders Ltd.; 2014
2. Atala A, Lanza R, Mikos T, Nerem R. Principles of regenerative medicine. 3rd edition, Academic Press, Elsevier Saunders Ltd.; 2018
3. Yuan CS, Bieber E, Bauer BA. Textbook of complementary and alternative medicine. 2nd edition, Informa Healthcare, NY.; 2006
4. Bhatt J, Bhat AR, Dhama K, Amarpal D. An overview of ozone therapy in equine-an emerging healthcare solution. Journal of Experimental Biology and Agricultural Science. 2016;4:S205-S210
5. Sciorsci RL, Lillo E, Occhiogrosso L, Rizzo A. Ozone therapy in veterinary medicine: A review. Research in Veterinary Science. 2020;130:240-246
6. Tsuzuki N, Endo Y, Kikkawa L, Korosue K, Kaneko Y, Kitauchi A, Torisu S. Effects of ozonated autohemotherapy on the antioxidant capacity of Thoroughbred horses. Journal of Veterinary Medicine and Science. 2015;77:1647-1650
7. Coelho CS, Abreu-Bernadi W, Ginelli AM, Spagnol T, Gardel LS, Souza VRC. Use of ozone therapy in chronic laminitis in a horse. Journal of Ozone Therapy. 2015;1:30-35
8. Ortved KF. Regenerative medicine and rehabilitation for tendinous and ligamentous injuries in sport horses. The Veterinary Clinics of North America: Equine practice. 2018;34:359-373
9. Textor J. Autologous biologic treatment for equine musculoskeletal injuries: platelet-rich plasma and il-1 receptor antagonist protein. The Veterinary Clinics of North America: Equine practice. 2011;27:275-298
10. Romero A, Barrachina L, Ranera B, Remacha AR, Moreno B, de Blas I, Sanz A, Vazquez FJ, Vitoria A, Junquera C, Zaragoza P, Rodellar C. Comparison of autologous bone marrow and adipose tissue derived mesenchymal stem cells, and platelet rich plasma, for treating surgically induced lesions of the equine superficial digital flexor tendon. Veterinary Journal. 2017;224:76-84
11. Schnabel LV, Sonea OH, Jacobson MS Fortier, LA. Effects of platelet rich plasma and acellular bone marrow on gene expression patterns and DNA content of equine suspensory ligament explant cultures. Equine Veterinary Journal. 2008;40(3):260-5
12. Castelijns G, Crawford A, Schaffer J, Ortolano GA, Beauregard T, Smith RKW. Evaluation of a filter-prepared platelet concentrate for the treatment of suspensory branch injuries horses. Vet Comp Orthop Traumatol. 2011;24:363–9
13. Scala M, Lenarduzzi S, Spagnolo F. Regenerative medicine for the treatment of Teno-desmic injuries of the equine. A series of 150 horses treated with platelet-derived growth factors. In Vivo. 2014;6:1119–11124
14. Spencer ND, Gimble JM, Lopez MJ. Mesenchymal stromal cells: past, present, and future. Veterinary Surgery. 2011;40:129-139
15. Youngstrom DW, Ladow JE, Barret JG. Tenogenesis of bone marrow-, adipose-, and tendon-derived stem cells in a dynamic bioreactor. Connective tissue research. 2016;7:125
16. Fu Y, Karbaat L, Wu L, Leijten J, Both SK, Karperien M. Trophic Effects of Mesenchymal Stem Cells in Tissue Regeneration. Tissue engineering: Part B Review. 2017;23:515-528
17. Cuomo AV, Virk M, Petrigliano F, Morgan EF, Lieberman J. Mesenchymal Stem Cell Concentration and Bone Repair: Potential Pitfalls from Bench to Bedside. The Journal of Bone and Joint Surgery. 2009;91(5):1073-832009
18. Ishikawa S, Horinouchi C, Murata D. Isolation and characterization of equine dental pulp stem cells derived from Thoroughbred wolf teeth. Journal of Veterinary Medical and Science. 2017;79:47-51
19. Bertone AL, Reisbig NA, Kilborne AH. Equine dental pulp connective tissue particles reduced lamness in horses in a controlled clinical trial. Frontier Veterinary Science. 2017;4:31
20. Burk J, Berner D, Brehm W, Hillmann A, Horstmeier C, Josten C, Paebst F, Rossi G, Schubert S, Ahrberg AB. Long-Term Cell Tracking Following Local Injection of Mesenchymal Stromal Cells in the Equine Model of Induced Tendon Disease. Cell Transplant. 2016;25:2199-2211
21. Godwin EE, Young NJ, Dudhia J, Beamish IC, Smith RKW. Implantation of bone marrow-derived mesenchymal stem cells demonstrates improved outcome in horses with overstrain injury of the superficial digital flexor tendon. Equine
22. Pacini S, Spinabella S, Trombi L, Fazzi R, Galimberti S, Dini F, Carlucci F, Petrini M. Suspension of bone marrow-derived undifferentiated mesenchymal stromal cells for repair of superficial digital flexor tendon in race horses. Tissue Engineering. 2007;13:2949-2955
23. Ho JOY, Sawadkar P, Mudera V. A review on the use of cell therapy in the treatment of tendon disease and injuries. Journal of Tissue Engineering. 2014;5:1-18
24. Witte TH, Yeager AE, Nixon AJ. Intralesional injection of insulin-like growth factor-I for treatment of superfacial digital flexor tendonitis in Thoroughbred racehorse: 40 cases (2000-2004). Journal of American Veterinary Medicine Association. 2011;234
25. Hortensius RA, Ebens JH, Harley BAC. Immunomodulatory effects of amniotic membrane matrix incorporated into collagen scaffolds. Journal of Biomedicine Material Research A. 2016;104:1332-1342
26. Gellhorn AC, Han A. The use of dehydrated human amnion/chorion membrane allograft injection for the treatment of tendinopathy or arthritis: a case series involving 40 patients. Physical Medicine and Rehabilitation. 2017;9:1236-1243
27. Clarke KL, Reardon R, Russell T. Treatment of osteochondrosis dissecans in the stifle
28. House AM, Morton A. Interleukin-1 receptor antagonist protein (IRAP( therapy for equine osteoarthritis. Extension file. College of Veterinary Medicine University of Florida. 2008
29. Tatarniuk DM, Groschen, DM, Merritt, KA, Maher MC, Ernst NS, Brown MP, Trumble TN. Discrepant Interleukin-1 receptor antagonist concentrations between serum and synovial fluid after intra-articular administration of Autologous Conditioned Serum into equine osteoarthritic distal interphalangeal joints. Orthopedic Research Seminar, Annual Meeting. 2016:0534
30. Zakirova E, Milomir K, Zhuravleva M, Rutland CS, Rizvanov A. Gene therapy as a modern method of treating naturally occurring tendinitis and desmitis in horses. IntechOpen Access, equine science. 2020;1-10
31. Kovac M, Litvin YA, Aliev RO, Zakirova EY, Rutland CS, Kiyasov AP. Gene therapy using plasmid DNA encoding vascular endothelial growth factor 164 and fibroblast growth factor 2 genes for the treatment of horse tendinitis and Desmitis: Case reports. Frontiers in Veterinary Science. 2017;4
32. Kovac M, Litvin YA, Aliev RO, Zakirova EY, Rutland CS, Kiyasov AP. Gene therapy using plasmid DNA encoding VEGF164 and FGF2 genes: A novel treatment of naturally occurring tendinitis and Desmitis in horses. Frontiers in Pharmacology. 2018;9
33. Pellegrini DZ, Muller TR, Fonteque JH, de Souza LP, de Souza AF, Joaquim JGF. Equine acupuncture methods and applications: A review. 2020;32:268-277
34. Michelotto J, Bastos PV, Sotomaior LF, Pimpao CT. Acupuncture diagnosis in equine stifle disease. Journal of Equine Veterinary Science. 2014;34:967-971
35. Wen TS. Acupuntura Classica Chinesa, 2nd edition, Cultrix, Sao Paulo; 2009
36. Silva MAH, Dorsher P.T. Neuroanatomic and clinical correspondences: acupuncture and vagus nerve stimulation. Journal of Alternative and Complementary Medicine. 2014;20:233-240
37. Dunning J, Butts R, Mourad F, Young I, Flannagan S, Perreault T. Dry needling: a literature review with implications for clinical practice guidelines. Physical Therapy Reviews. 2014;19:252-265
38. International Veterinary Acupuncture Society. https://www.med-vetacupuncture.org/english/vet/horse4.htm
39. Rogers P. Gold bead implantation (GBI) in dogs: Good medicine or malpractice? Medical Acupuncture Web Page. https://www.med-vetacupuncture.org/english/articles/hipbead.html. 2009
40. Pluim M, Martens A, Vanderperren K, van Weeren R, Oosterlinck M, Dewulf J, Kichouh M, Van Thielen B, Koene HW, Luciani A, Plancke L, Delesalle C. High-Power Laser Therapy Improves Healing of the Equine Suspensory Branch in a Standardized Lesion Model. Frontier Veterinary Science. 2020. https://doi.org/10.3389/fvets.2020.00600
41. Zielinska P, Nicpon J, Kielbowicz Z, Soroko M, Dudek K, Zaborski D. Effects of High Intensity Laser Therapy in the Treatment of Tendon and Ligament Injuries in Performance Horses. Animals. 2020;10:1327
42. Coombs R, Zhou S, Schaden W. Musculoskeletal Shockwave Therapy. Greenwich Medical Media, Valley Stream, New York. 2000
43. Yocom AF, Bass LD. Review of the application and efficacy of extracorporeal shockwave therapy in equine tendon and ligament injuries. Equine Veterinary Education. 2019;31:271-277
44. Waugh CM, Morrissey D, Jones E, Riley GP, Langberg H, Screen HR. In vivo biological response to extracorporeal shockwave therapy in human tendinopathy. European Cells and Materials. 2015;29:268-280
45. Loske AM. Shock waves as used in biomedical applications. In: Medical and Biomechanical Applications of Shock Waves. Springer, Cham, Switzerland. 2017;19-33, 189-203
