فهرست مقالات curcumin

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  1 - The effect of aerobic training and curcumin supplementation on the expression of IGF-1 gene in muscle rat
  Masoumeh Hosseini Hamid   Vakilian
  10.52547/jspac.39048.3.7.12
  Background: The purpose of this research was to investigate the effect of four weeks of moderate aerobic training and nanocurcumin supplementation on IGF-1 gene expression and its receptor in the soleus muscle of rats. Materials and Methods: 32 male Wistar rats, approx چکیده کامل

  Background: The purpose of this research was to investigate the effect of four weeks of moderate aerobic training and nanocurcumin supplementation on IGF-1 gene expression and its receptor in the soleus muscle of rats. Materials and Methods: 32 male Wistar rats, approximately eight weeks old, with a weight range of 200±10 grams, were prepared and kept for one week under standard conditions of light, temperature, and humidity. Rats were randomly divided into 4 groups of 8 series: healthy control group, aerobic training group, nanocurcumin group and aerobic training + nanocurcumin group. The training protocol was for 4 weeks, 5 days a week, in the first week, 20 minutes of activity with a speed of 18 meters per minute, and finally in the 4th week, it reached 35 minutes of activity with a speed of 20 meters per minute. Nanocurcumin supplement was also used for each animal at 80 mg / kilogram of body weight. One-way analysis of variance and Bonferroni's post hoc test was used at the significance level (P<0.05). Results: The results showed an increase in IGF-1 and IGF-1R gene expression levels in the soleus muscle in all groups compared to the control group. Conclusion: The combination of training and nanocurcumin supplementation probably increases the antioxidant capacity of the body and causes a greater increase in the expression of the IGF-1 gene and IGF-1R in skeletal muscles, which indicates more anabolic effects. پرونده مقاله
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  2 - The Effect of an Aerobic Training Course with Curcumin Supplementation on Serum Lipid Profile in Obese Male Rats
  Somayeh   Sadeghnia Abbas  Fattahi Bafghi Narges   shishebori
  Background: Today, research has shown that the combination of physical activity and supplements can have more beneficial effects on diseases, so the purpose of this study is to investigate the effect of a period of aerobic training combined with consumption Curcumin sup چکیده کامل

  Background: Today, research has shown that the combination of physical activity and supplements can have more beneficial effects on diseases, so the purpose of this study is to investigate the effect of a period of aerobic training combined with consumption Curcumin supplement is based on serum lipid profile of obese rats. Materials and Methods: In a semi-experimental and applied study, 32 obese male rats of 6 months with Wistar breed with a weighted average of 332/28 Grams and standard deviation of 9 after 7 days of acquaintance with the laboratory environment were randomly divided into 4 groups of 8 (control, training, supplement and training-supplement). The training-supplementation and training groups underwent aerobic training for 6 weeks and 4 sessions in each week, according to the training protocol. Supplement and training- Supplements Groups also for 6 weeks and 4 meals every week, one hour before the start of training, 50 mg of curcumin per kilogram of body weight was gavage. 24 hours after the last training session, while fasting for 12 hours, all subjects were anesthetized with ketamine and xylazine solution and blood was taken from the posterior orbital sinus of the rats. The collected blood samples were immediately transferred to the laboratory to measure the variables. In order to analyze the data at the descriptive level, mean and standard deviation tests were used, and at the inferential level, the Shapiro-Wilk test was used to check the normality of the data, and the two-way ANOVA test was used to check the interaction effect of the groups. data analysis It was done with using spss software version 26 and at a significance level (P≤0.05). Results: The results of the research showed that a course of aerobic training and curcumin supplementation had a significant effect on TG and HDL of obese rats. It was also observed that a course of aerobic training and curcumin supplementation had no significant effect on TC and LDL of obese rats. Conclusion: The results showed that aerobic training and curcumin supplementation can be used simultaneously to improve the lipid profile of obese people, especially in HDL and TG indices پرونده مقاله