مروری بر حسگر پلیمرهای قالب مولکولی بر پایه نقاط کوانتومی گرافن
محورهای موضوعی :سید محمد رضا میلانی حسینی 1 , پریزاد محمدنژاد 2 , الهه جباری 3
1 - دانشكده شيمي
2 - دانشكده شيمي
3 - دانشكده شيمي
کلید واژه: نقاط کوانتومی گرافن پلیمرهای قالب مولکولی حسگر,
چکیده مقاله :
بخش مهم فرآیندها در شناسایی علائم مولکولی با روش های آزمایشگاهی پیچیده انجام می شود. آنچه امروزه قابل مشاهده است، مربوط به بهره برداری از دستاوردها و ترکیب آن ها به عنوان، فناوری های جدید قابل دسترس می باشند. انجام این هدف نیازمند پیشرفت فناوری های 100-1 نانومتر می باشد تا بتوانند در تجسم و حس برهمکنش های بین گیرنده ها و اجزای خاص کمک کند. نقاط کوانتومی گرافن با سهولت تولید و زیست سازگاری و سمیت کم قابل استفاده این در همه زمینه ها شده است. این نوع نقاط کوانتومی، حاوی گروه های عاملی کربوکسیلیک اسید در سطح خود هستند که قابلیت تعویض با گروه های عاملی دیگر را داشته و موجب حلالیت بسیار بالا آن ها در آب شده است. همچنین آن-ها را برای عامل دار کردن با مواد آلی مختلف مثل پلیمرها، مناسب کرده است. قالبگیــری مولکولــی روشی ســریع و دقیــق بــرای تشــخیص مولكولها و یکــی از مهمتریــن روشهــای تشــخیص و تعییــن کمــی آنها می باشد. استفاده از حسگر پلیمرهای قالب مولکولی بر پایه نقاط کوانتومی گرافن به جهت گزینش پذیری و حساسیت بالا و همچنین قابلیت انحلال در محیط های آبی، موجب عملکرد بالای آن ها استفاده در اکثر زمینه های تشخیص و اندازه گیری شده است.
An important part of molecular markers identification has been performed by sophisticated laboratory methods. What is visible today is referred to exploit the achievements and combine them as new available technologies. To accomplish this gold, we need to develop technologies of 1 to 100 nm to help imagine and sense the interactions between the receptors and specific components. Graphene quantum dots have been developed with easy production methods, biocompatibility, and low toxicity and have been applicable in all fields. This type of quantum dots contains carboxylic acid functional groups on their surfaces, which are interchangeable with other functional groups and have a high solubility in water. It also makes them appropriate for functionalizing with various organic materials such as polymers. Molecular imaging is a fast and accurate method for molecule detection and it is one of the most important methods for molecule detection and quantification. Molecularly imprinted polymer based on graphene quantum dots have being had high-performance applications in most fields of detection and measurement, due to their high selectivity and sensitivity as well as solubility in aqueous media.
[1] B. Zheng, H. Fu, J. P. Berry, and B. McCord, “A rapid method for separation and identification of microcystins using
capillary electrophoresis and time-of-flight mass spectrometry,” J. Chromatogr. A, vol. 1431, pp. 205–214, 2016. [2] D. Mendil, Z. Demirci, O. D. Uluozlu, M. Tuzen, and M. Soylak, “A new separation and preconcentration method for selenium in some foods using modified silica gel with 2,6-diamino-4-phenil-1,3,5-triazine,” Food Chem., vol. 221,
pp. 1394–1399, 2017. [3] M. A. Farajzadeh, B. Feriduni, and M. R. Afshar Mogaddam, “Development of a new extraction method based on counter current salting-out homogenous liquid-liquid extraction followed by dispersive liquid-liquid microextraction: Application for the extraction and preconcentration of widely used pesticides from fruit ,” Talanta, vol. 146,
pp. 772–779, 2016. [4] T. A. Sandvik, A. Husa, M. Buchmann, and E. Lundanes, “Routine Supercritical Fluid Chromatography Tandem Mass Spectrometry Method for Determination of Vitamin K1 Extracted from Serum with a 96-Well Solid-Phase Extraction Method,” J. Appl. Lab. Med. An AACC Publ.,
vol. 1, no. 6, pp. 637–648, 2017. [5] Y. Hernández, M. G. Lobo, and M. González, “Determination of vitamin C in tropical fruits: A comparative evaluation of
methods,” Food Chem., vol. 96, no. 4, pp. 654–664, 2006. [6] H. Li, Z. Kang, Y. Liu, and S. T. Lee, “Carbon nanodots: Synthesis, properties and applications,” J. Mater. Chem., vol. 22, no. 46,
pp. 24230–24253, 2012. [7] X. Michalet et al., “Quantum dots for live cells, in vivo imaging, and diagnostics,” Science (80-. )., vol. 307, no. 5709, pp.
538–544, 2005. [8] D. Pacheco-Alvarez, R. S. Solórzano-Vargas, and A. L. Del Río, “Biotin in metabolism and its relationship to human disease,” Arch. Med. Res.,
vol. 33, no. 5, pp. 439–447, 2002. [9] A. Cayuela, M. L. Soriano, C. Carrillo-Carrión, and M. Valcárcel, “Semiconductor and carbon-based fluorescent nanodots: The need for consistency,” Chem. Commun.,
vol. 52, no. 7, pp. 1311–1326, 2016. [10] M. Holzinger, A. Le Goff, and S. Cosnier, “Nanomaterials for biosensing applications: A review,” Front. Chem., vol. 2, no. AUG,
pp. 1–10, 2014. [11] S. Zhu et al., “Surface chemistry routes to modulate the photoluminescence of graphene quantum dots: From fluorescence mechanism to up-conversion bioimaging applications,” Adv. Funct. Mater., vol. 22, no. 22,
pp. 4732–4740, 2012. [12] J. C. Bonilla, F. Bozkurt, S. Ansari, N. Sozer, and J. L. Kokini, “Applications of quantum dots in Food Science and
biology,” Trends Food Sci. Technol., vol. 53, pp. 75–89, 2016. [13] J. K. Jaiswal and S. M. Simon, “Potentials and pitfalls of fluorescent quantum dots for biological imaging,” Trends Cell Biol., vol. 14, no. 9,
pp. 497–504, 2004. [14] S. Bak, D. Kim, and H. Lee, “Graphene quantum dots and their possible energy applications: A review,” Curr. Appl.
Phys., vol. 16, no. 9, pp. 1192–1201, 2016. [15] D. Pan, J. Zhang, Z. Li, and M. Wu, “Hydrothermal route for cutting graphene sheets into blue-luminescent graphene quantum dots,” Adv. Mater., vol. 22, no. 6,
pp. 734–738, 2010. [16] Y. Li et al., “An electrochemical avenue to green-luminescent graphene quantum dots as potential electron-acceptors for photovoltaics,” Adv. Mater., vol. 23, no. 6,
pp. 776–780, 2011. [17] J. Shen, Y. Zhu, X. Yang, and C. Li, “Graphene quantum dots: Emergent nanolights for bioimaging, sensors, catalysis and photovoltaic devices,” Chem. Commun., vol. 48, no. 31,
pp. 3686–3699, 2012. [18] S. Chen, X. Hai, C. Xia, X. W. Chen, and J. H. Wang, “Preparation of excitation-independent photoluminescent graphene quantum dots with visible-light excitation/emission for cell imaging,” Chem. - A Eur. J., vol. 19, no. 47,
pp. 15918–15923, 2013. [19] Y. Sun et al., “Large scale preparation of graphene quantum dots from graphite with tunable fluorescence properties,” Phys. Chem. Chem. Phys., vol. 15, no. 24,
pp. 9907–9913, 2013. [20] M. Mehrzad-Samarin, F. Faridbod, A. S. Dezfuli, and M. R. Ganjali, “A novel metronidazole fluorescent nanosensor based on graphene quantum dots embedded silica molecularly imprinted polymer,” Biosens. Bioelectron., vol. 92, no.
August, pp. 618–623, 2017. [21] H. Chen, L. Lin, H. Li, and J. M. Lin, “Quantum dots-enhanced chemiluminescence: Mechanism and application,” Coord. Chem. Rev.,
vol. 263–264, no. 1, pp. 86–100, 2014. [22] D. R. Kryscio and N. A. Peppas, “Critical review and perspective of macromolecularly imprinted polymers,” Acta Biomater., vol. 8,
no. 2, pp. 461–473, 2012. [23] Y. Fuchs, O. Soppera, and K. Haupt, “Photopolymerization and photostructuring of molecularly imprinted polymers
for sensor applications-A review,”Anal. Chim. Acta, vol. 717, pp. 7–20, 2012. [24] G. Guan, B. Liu, Z. Wang, and Z. Zhang, “Imprinting of molecular recognition sites on nanostructures and its applications in chemosensors,” Sensors, vol. 8, no. 12,
pp. 8291–8320, 2008. [25] A. Sassolas, B. Prieto-Simón, and J.-L. Marty, “Biosensors for Pesticide Detection: New Trends,” Am. J. Anal. Chem., vol. 03, no. 03,
pp. 210–232, 2012. [26] E. Turiel and A. Martín-Esteban, “Molecularly imprinted polymers for sample preparation: A review,” Anal. Chim. Acta, vol. 668, no. 2,
pp. 87–99, 2010. [27] A. Martín-Esteban, “Molecularly-imprinted polymers as a versatile, highly selective tool in sample preparation,” TrAC - Trends Anal. Chem., vol. 45, no. 1,
pp. 169–181, 2013. [28]
Z. H. Meng, Molecularly Imprinted Sol-Gel Sensors. 2012. [29] S. N. Tan, “Biosensors Based on Sol – Gel-Derived Materials,”
pp. 471–489, 2011. [30] Y. Zhou, S. K. Sharma, Z. Peng, and R. M. Leblanc, “Polymers in carbon dots: A review,” Polymers (Basel)., vol. 9, no. 2,
p. 67, 2017.
