• فهرس المقالات Glucose

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        1 - High intensity interval training and Eryngium billardieri extract consumption on MMP-2 gene expression of visceral fat in rats with metabolic syndrome
        Mostafa  Haji Gholami Shahin Riyahi Malayeri Asal   ziloubaf Hedyeh Hassanpour
        Background: Metabolic syndrome includes a set of metabolic disorders that expose the patient to cardiovascular disease and diabetes. The aim of the present study was to evaluate the effect of High intensity interval training and Eryngium billardieri extract consumptio أکثر
        Background: Metabolic syndrome includes a set of metabolic disorders that expose the patient to cardiovascular disease and diabetes. The aim of the present study was to evaluate the effect of High intensity interval training and Eryngium billardieri extract consumption on the expression of visceral fat matrix metalloproteinase-2 gene and insulin resistance in rats with metabolic syndrome. Methods: In this experimental study, 32 male Sprague-Dawley rats weighing 200-250 g were randomly divided into 4 groups: 1- Healthy group 2- Metabolic syndrome 3- Metabolic syndrome + Eryngium billardieri 4- Metabolic syndrome + Eryngium billardieri + HIIT. The training protocol was performed on a rodent treadmill for 8 weeks and 5 sessions per week and 125 mg of Eryngium billardieri extract per kilogram of body weight was given by gastric gavage 5 days a week for 8 weeks. At the end of the eighth week, sample of visceral adipose tissue was taken to examine the expression of MMP-2 gene. Animal blood was collected from the heart. ANOVA were used for data analysis using SPSS 23 software at a significant level (p <0.05). Tukey significance test was used to compare significant differences. Results: Eight weeks of intense intermittent exercise with consumption of Eryngium billardieri extract caused a significant decrease in MMP-2 gene levels and glucose and insulin levels in comparison with the metabolic syndrome group (P <0.05). Conclusion: According to the results of the study, it seems that High intensity interval training with the use of Eryngium billardieri extract helps to improve insulin resistance and reduce MMP2. تفاصيل المقالة
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        2 - Relationship between erythropoietin and fasting glucose glucose after a resistance training program in male Wistar rats with type 2 diabetes
        Farshad   Sadeghi Yaser Kazemzadeh Abdolali  Banaeifar Sajad Arshadi
        Background: Erythropoietin is known as a strong stimulant in the activation of satellite cells and increasing the regeneration function of muscle tissue. The purpose of this study was to investigate the relationship between erythropoietin concentration and fasting blood أکثر
        Background: Erythropoietin is known as a strong stimulant in the activation of satellite cells and increasing the regeneration function of muscle tissue. The purpose of this study was to investigate the relationship between erythropoietin concentration and fasting blood glucose after a resistance training program in male Wistar rats with type 2 diabetes. Materials and Methods: Twenty-four male rats aged 6 weeks were divided into 3 groups: healthy control (n=8), diabetic control (n=8) and resistance training (n=8). Resistance exercises were performed for 8 weeks, 5 sessions per week, with an intensity of 100-30% of the weight of the rats in the resistance training group. In the last week of the training program, the maximum oxygen consumption of the rats was taken using the executive protocol on the rat treadmill. 48 hours after finishing the training program, blood samples were taken from the right ventricle of heart of the rats and erythropoietin and fasting blood glucose were evaluated. The data was statistically analyzed using Pearson's correlation and one-way analysis of variance at the alpha level of less than 0.05. Results: The results showed that there is no significant relationship between erythropoietin and fasting blood glucose among any of the groups. Also, performing 8 weeks of resistance training in diabetic rats led to an increase in erythropoietin concentration (P≤0.0001) and a decrease in blood glucose (P≤0.0001). Conclusion: It seems that more stimulation of EPO and regeneration of muscle tissue as well as increased energy consumption in muscle tissue is one of the possible mechanisms of blood glucose reduction caused by 8 weeks of resistance training in diabetic rats تفاصيل المقالة