تاثیر مواد معدنی بر سلامت سم
الموضوعات :فاطمه کهنسال 1 , مرضیه فائزی 2
1 - دانشجو، گروه علوم درمانگاهی، دانشکده دامپزشکی، دانشگاه فردوسی، مشهد
2 - دانشجو، گروه بهداشت مواد غذایی، دانشکده دامپزشکی، دانشگاه تهران، تهران
الکلمات المفتاحية: سم, کراتینه شدن, مواد معدنی شلاته شده, مس, روی,
ملخص المقالة :
کیفیت سم به عنوان مجموعهای از ویژگیهای بافت شاخی سم، شکل سم و آناتومی و فیزیولوژی ساختار داخلی سم شناخته میشود و سلامت سم به نوبه خود با تولید بافت شاخی مقاوم و با کیفیت تعیین میشود. یکپارچگی عملکردی بافت شاخی سم اساساً به تمایز مناسب، یعنی کراتینه شدن سلولهای اپیدرمی سم بستگی دارد. کنترل و تعدیل کراتینه شدن اپیدرم سم توسط انواع مولکولها و هورمونها صورت میگیرد. این فرآیند به تامین مناسب مواد مغذی از جمله ویتامینها، مواد معدنی و عناصر کمیاب بستگی دارد. تنظیم و کنترل تمایز و جریان مواد مغذی به سلولهای اپیدرمی نقش اساسی در تعیین کیفیت و در نتیجه یکپارچگی عملکردی بافت شاخی سم دارد. کاهش عرضه مواد مغذی به سلولهای اپیدرمی کراتینهکننده منجر به تولید بافت شاخی با کیفیت پایینتر و افزایش حساسیت آن به آسیبهای شیمیایی، فیزیکی یا میکروبی محیط میشود. شواهد زیادی نشان میدهد که هورمونها، ویتامینها، مواد معدنی و عناصر کمیاب نقش مهمی در رشد طبیعی بافت شاخی سم و تشکیل صحیح کراتین دارند. افزایش فراهمی زیستی مواد معدنی کمیاب، استفاده از آنها را بهبود میبخشد و میتواند به بهبود یکپارچگی بافتهای کراتینه شده کمک کند.
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