The effect of 8 weeks of aerobic training and resveratrol consumption on the indicators of metabolic syndrome in overweight women
محورهای موضوعی : تغذیه ورزشی
Masoumeh Hosseini
1
(Associate Prof., Dept. of Exercise Physiology, Faculty of Human Sciences, East Tehran Branch, Islamic Azad University, Tehran, Iran)
Sahar Esmaeli Dorani
2
(M.Sc Student of Exercise Physiology, Faculty of Human Sciences, East Tehran Branch, Islamic Azad University, Tehran, Iran )
کلید واژه: Resveratrol, Aerobic training, Metabolic syndrome, Overweight,
چکیده مقاله :
Background: Metabolic syndrome is a set of risk factors for cardiovascular disease and type 2 diabetes. The purpose of this study was to investigate the effect of 8 weeks of aerobic training and resveratrol consumption on the indicators of metabolic syndrome in overweight women. Materials and Methods: In this quasi-experimental study, 32 women with metabolic syndrome with body mass index of 25-29 / 29 were purposefully selected and randomly divided into four groups (8 people): aerobic training, resveratrol supplementation, training + supplementation and control. The training protocol was performed on a treadmill for 8 weeks with 3 sessions of 60 minutes per week, with an intensity of 75-60% of the heart rate. The supplement groups took one capsule containing 400 mg of resveratrol daily. Blood sampling was performed before the start of the research protocol and 48 hours after the last training session. Analysis of covariance and Bonferroni post hoc test were used (P ≤ 0.05). Results: The results showed that aerobic training with supplementation led to a significant decrease in waist circumference, blood pressure, fasting blood sugar, triglycerides, total cholesterol and LDL and a significant increase in maximal oxygen consumption (P = 0.001). Conclusion: Based on the results of the study, taking resveratrol supplementation along with aerobic training can have a positive effect on the indicators of metabolic syndrome. It is recommended to use aerobic training and resveratrol supplement to improve the physical condition of overweight women.
Background: Metabolic syndrome is a set of risk factors for cardiovascular disease and type 2 diabetes. The purpose of this study was to investigate the effect of 8 weeks of aerobic training and resveratrol consumption on the indicators of metabolic syndrome in overweight women. Materials and Methods: In this quasi-experimental study, 32 women with metabolic syndrome with body mass index of 25-29 / 29 were purposefully selected and randomly divided into four groups (8 people): aerobic training, resveratrol supplementation, training + supplementation and control. The training protocol was performed on a treadmill for 8 weeks with 3 sessions of 60 minutes per week, with an intensity of 75-60% of the heart rate. The supplement groups took one capsule containing 400 mg of resveratrol daily. Blood sampling was performed before the start of the research protocol and 48 hours after the last training session. Analysis of covariance and Bonferroni post hoc test were used (P ≤ 0.05). Results: The results showed that aerobic training with supplementation led to a significant decrease in waist circumference, blood pressure, fasting blood sugar, triglycerides, total cholesterol and LDL and a significant increase in maximal oxygen consumption (P = 0.001). Conclusion: Based on the results of the study, taking resveratrol supplementation along with aerobic training can have a positive effect on the indicators of metabolic syndrome. It is recommended to use aerobic training and resveratrol supplement to improve the physical condition of overweight women.
(1). Hosseinpanah F, Barzin M, Eskandary PS, Mirmiran P, Azizi F. Trends of obesity and abdominal obesity in Tehranian adults: a cohort study. BMC Public Health. 2009 Nov 23;9:426. doi: 10.1186/1471-2458-9-426. PMID: 19930614; PMCID: PMC2801677.
(2). Kearns K, Dee A, Fitzgerald AP, Doherty E, Perry IJ. Chronic disease burden associated with overweight and obesity in Ireland: the effects of a small BMI reduction at population level. BMC Public Health. 2014 Feb 10;14:143. doi: 10.1186/1471-2458-14-143. PMID: 24512151; PMCID: PMC3929131.
(3). Wadden TA, Webb VL, Moran CH, Bailer BA. Lifestyle modification for obesity: new developments in diet, physical activity, and behavior therapy. Circulation. 2012 Mar 6;125(9):1157-70. doi: 10.1161/CIRCULATIONAHA.111.039453. PMID: 22392863; PMCID: PMC3313649.
(4). Eriksson J, Taimela S, Koivisto VA. Exercise and the metabolic syndrome. Diabetologia. 1997 Feb;40(2):125-35. doi: 10.1007/s001250050653. PMID: 9049471.
(5). Ebrahimi H, Emamian MH, Shariati M, Hashemi H, Fotouhi A. Metabolic syndrome and its risk factors among middle aged population of Iran, a population based study. Diabetes Metab Syndr. 2016 Jan-Mar;10(1):19-22. doi: 10.1016/j.dsx.2015.08.009. Epub 2015 Aug 21. PMID: 26341930.
(6). Attarzadeh Hoseini S.R ؛ Rahimiyan Mashhad Z .Comparison the effect of aerobic training and diet on Body Composition and Metabolic Syndrome Indexes in overweight and obese women. Applied research in sport management .2012; 2:22-36.
(7). Das S, Alagappan VK, Bagchi D, et al. Coordinated induction of iNOS-VEGF-KDR-eNOS after resveratrol consumption: a potential mechanism for resveratrol preconditioning of the heart. Vascular Pharmacology. 2005 Apr-May;42(5-6):281-289. DOI: 10.1016/j.vph.2005.02.013. PMID: 15905131.
(8). Malekyian-Fini E, Kaviani-Nia A, Mahmoudi F. The interactive effect of aerobic training and resveratrol supplementation on C-reactive protein and metabolic profiles in women with type 2 diabetes. Feyz. 2015; 19 (5) :372-381
URL: http://feyz.kaums.ac.ir/article-1-2858-en.html
(9). Asad.M.The effect of eight weeks of aerobic, resistance and combined training on HDL, LDL cholesterol and cardiorespiratory fitness in obese men. Applied research in management and life sciences in sports. 2011; 3:57-64.
(10). Mirzaei.B.Rahmaninia, F.Mehrabani,J.Determining the validity of Bruce and Concaney tests by gas analyzer method in estimating VO2MAX of national team wrestlers.Harekat.2006;9(29):1-11.
(11). Atashak S, Batourak K, Azizbeigi K. The effect of moderate-intensity aerobic exercise training on metabolic syndrome factors and acylated ghrelin in middle- age women. RJMS. 2017; 24 (159) :10-20
URL: http://rjms.iums.ac.ir/article-1-4715-en.html
(12). Ebrahimi H, Emamian MH, Shariati M, Hashemi H, Fotouhi A. Metabolic syndrome and its risk factors among middle aged population of Iran, a population based study. Diabetes Metab Syndr. 2016 Jan-Mar;10(1):19-22. doi: 10.1016/j.dsx.2015.08.009. Epub 2015 Aug 21. PMID: 26341930.
(13). Taghian F, Zolfaghari M. Effect of 12 week aerobic exercise on the obestatin level in obese women. jmj. 2013; 11 (4) :1-8
URL: http://jmj.jums.ac.ir/article-1-305-en.html
(14). Duncan GE, Anton SD, Sydeman SJ, Newton RL Jr, Corsica JA, Durning PE, Ketterson TU, Martin AD, Limacher MC, Perri MG. Prescribing exercise at varied levels of intensity and frequency: a randomized trial. Arch Intern Med. 2005 Nov 14;165(20):2362-9. doi: 10.1001/archinte.165.20.2362. PMID: 16287765.
(15). Sung KC, Ryu SH. Insulin resistance, body mass index, waist circumference are independent risk factor for high blood pressure. Clin Exp Hypertens. 2004 Aug;26(6):547-56. doi: 10.1081/ceh-200031833. PMID: 15554457.
(16). Baharloo S, Taghiyan F, Hedayati M. Effect of aerobic exercise on glucose, insulin and insulin resistance in subclinical hypothyroidism overweight-obese women. RJMS. 2014; 21 (125) :75-84
URL: http://rjms.iums.ac.ir/article-1-3416-en.html
(17). Ross R, Dagnone D, Jones PJ, Smith H, Paddags A, Hudson R, Janssen I. Reduction in obesity and related comorbid conditions after diet-induced weight loss or exercise-induced weight loss in men. A randomized, controlled trial. Ann Intern Med. 2000 Jul 18;133(2):92-103. doi: 10.7326/0003-4819-133-2-200007180-00008. PMID: 10896648.
(18). Babaei P, Azali Alamdari K, Soltani Tehrani B, Damirchi A. Effect of six weeks of endurance exercise and following detraining on serum brain derived neurotrophic factor and memory performance in middle aged males with metabolic syndrome. J Sports Med Phys Fitness. 2013 Aug;53(4):437-43. PMID: 23828292.
(19). Faghihzadeh F, Adibi P, Hekmatdoost A. The effects of resveratrol supplementation on cardiovascular risk factors in patients with non-alcoholic fatty liver disease: a randomised, double-blind, placebo-controlled study. Br J Nutr. 2015 Sep 14;114(5):796-803. doi: 10.1017/S0007114515002433. Epub 2015 Aug 3. PMID: 26234526.
(20). Azali Alamdari K, khalafi M, Ghorbanian B. Effect of Aerobic Training on Serum Adiponectin and Ctrp-3 in Males with Metabolic Syndrome. Iranian Journal of Endocrinology and Metabolism. 2017; 18 (5) :368-377
URL: http://ijem.sbmu.ac.ir/article-1-2126-en.html.
(21). Balducci S, Zanuso S, Nicolucci A, Fernando F, Cavallo S, Cardelli P, Fallucca S, Alessi E, Letizia C, Jimenez A, Fallucca F, Pugliese G. Anti-inflammatory effect of exercise training in subjects with type 2 diabetes and the metabolic syndrome is dependent on exercise modalities and independent of weight loss. Nutr Metab Cardiovasc Dis. 2010 Oct;20(8):608-17. doi: 10.1016/j.numecd.2009.04.015. Epub 2009 Aug 19. PMID: 19695853.
(22). Stevens VJ, Obarzanek E, Cook NR, Lee IM, Appel LJ, Smith West D, Milas NC, Mattfeldt-Beman M, Belden L, Bragg C, Millstone M, Raczynski J, Brewer A, Singh B, Cohen J; Trials for the Hypertension Prevention Research Group. Long-term weight loss and changes in blood pressure: results of the Trials of Hypertension Prevention, phase II. Ann Intern Med. 2001 Jan 2;134(1):1-11. doi: 10.7326/0003-4819-134-1-200101020-00007. PMID: 11187414.
(23). Sugiura H, Sugiura H, Kajima K, Mirbod SM, Iwata H, Matsuoka T. Effects of long-term moderate exercise and increase in number of daily steps on serum lipids in women: randomised controlled trial [ISRCTN21921919]. BMC Womens Health. 2002;2(1):3. doi: 10.1186/1472-6874-2-3. PMID: 11846892; PMCID: PMC65683.
(24). Wilund KR, Feeney LA, Tomayko EJ, Weiss EP, Hagberg JM. Effects of endurance exercise training on markers of cholesterol absorption and synthesis. Physiol Res. 2009;58(4):545-552. doi: 10.33549/physiolres.931515. Epub 2008 Jul 25. PMID: 18656998.
(25). Dong HH, Ren HL. New progression in the study of protective properties of resveratrol in anticardiovascular disease. Bratisl Lek Listy. 2004;105(5-6):225-9. PMID: 15535114.
(26). Vahedi M. The beneficial effects of Resvin supplementation with active ingredient resveratrol in prevention and improved treatment of some diseases Geymonat. TTD 2011; 11(2): 5-6.
(27). Okawara M, Katsuki H, Kurimoto E, Shibata H, Kume T, Akaikea A. Resveratrol protects dopaminergic neurons in midbrain slice culture from multiple insults. Biochem Pharmacol 2007; 73(4): 550-60.
(28). Pallàs M, Casadesús G, Smith MA, Coto- Montes A, Pelegri C, Vilaplana J, et al. Resveratrol and neurodegenerative diseases: Activation of SIR1 as the potential pathway towards neuroprotection. Curr Neurovasc Res 2009; 6(1): 70-81.
